N-(1-aminobutyl)pyridine-3-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-(1-aminobutyl)pyridine-3-carboxamide
• 化学式: C₁₀H₁₅N₃O
• 分子量: 193.25
• InChiKey: QRZWDULVGSZYKJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  68
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• AMINE FUNCTIONAL POLYAMIDES
  申请人：GENZYME CORPORATION

  公开号：US20160208046A1

  公开（公告）日：2016-07-21

  Amine functional polyamides comprise amine and ammonium groups along the polymer chain. Amine functional polyamides can be used as pharmaceutical agents and in pharmaceutical compositions. The amine functional polyamides are particularly useful in the treatment or prevention of mucositis and infection, specifically oral mucositis, surgical site infection, and lung infection associated with cystic fibrosis.

  氨基官能团聚酰胺是由氨基和铵基团组成的高分子链。氨基官能团聚酰胺可用作制药剂和制药组合物。氨基官能团聚酰胺在治疗或预防粘膜炎和感染方面特别有用，尤其是口腔粘膜炎、手术部位感染和与囊性纤维化相关的肺部感染。
• Antimicrobial polyamide compositions and mastitis treatment
  申请人：Merial Limited

  公开号：US10131744B2

  公开（公告）日：2018-11-20

  The present invention relates to veterinary compositions and methods of treating and/or preventing mastitis in non-human mammals. More particularly, the present invention relates to the treatment of mastitis in cows. The veterinary composition comprises a water soluble, locally-acting, antimicrobial amine functional polyamide polymer.

  本发明涉及治疗和/或预防非人类哺乳动物乳腺炎的兽药组合物和方法。更具体地说，本发明涉及奶牛乳腺炎的治疗。该兽用组合物包括一种水溶性、局部作用的抗菌胺功能聚酰胺聚合物。
• Amine functional polyamides
  申请人：GENZYME CORPORATION

  公开号：US10113032B2

  公开（公告）日：2018-10-30

  Amine functional polyamides comprise amine and ammonium groups along the polymer chain. Amine functional polyamides can be used as pharmaceutical agents and in pharmaceutical compositions. The amine functional polyamides are particularly useful in the treatment or prevention of mucositis and infection, specifically oral mucositis, surgical site infection, and lung infection associated with cystic fibrosis.

  胺功能聚酰胺由聚合物链上的胺和铵基团组成。胺功能聚酰胺可用作药剂和药物组合物。胺功能聚酰胺尤其适用于治疗或预防粘膜炎和感染，特别是口腔粘膜炎、手术部位感染以及与囊性纤维化相关的肺部感染。
• ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT
  申请人：Boehringer Ingelheim Animal Health USA Inc.

  公开号：EP2968231B1

  公开（公告）日：2020-07-01
• US20140271526A1
  申请人：——

  公开号：US20140271526A1

  公开（公告）日：2014-09-18