4-[(2-Aminophenyl)methyl]-2-methoxyphenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[(2-Aminophenyl)methyl]-2-methoxyphenol
• 英文别名: 4-[(2-aminophenyl)methyl]-2-methoxyphenol
• 化学式: C₁₄H₁₅NO₂
• 分子量: 229.27
• InChiKey: GSWIHGFYFQBSOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  55.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] AUGMENTING MOIETIES FOR ANTI-INFLAMMATORY COMPOUNDS<br/>[FR] AUGMENTATION DE FRACTIONS POUR DES COMPOSÉS ANTI-INFLAMMATOIRES
  申请人：UNIV RUTGERS

  公开号：WO2014144073A2

  公开（公告）日：2014-09-18

  Augmented or synergized anti-inflammatory constructs are disclosed including terpenes covalently conjugated with other anti-inflammatory molecules such as nonsteroidal anti-inflammatory drugs, vanilloids, amino acids and polyamines; and anti-inflammatory molecules covalently conjugated with specific amino acids. For the latter, further conjugation with a choline bioisostere further augments the anti-inflammatory activity.