N-[4-(2-sulfanylideneethyl)phenyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[4-(2-sulfanylideneethyl)phenyl]acetamide
• 化学式: C₁₀H₁₁NOS
• 分子量: 193.27
• InChiKey: JAOLUGFGCDRTHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  61.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES<br/>[FR] MOLÉCULES BIOLOGIQUEMENT ACTIVES, LEURS CONJUGUÉS, ET UTILISATIONS THÉRAPEUTIQUES
  申请人：REGENERON PHARMA

  公开号：WO2014145090A1

  公开（公告）日：2014-09-18

  The present disclosure relates to linker compounds that are useful in covalently linking biologically active molecules with Ligands. The disclosed compounds also relate to biologically active molecules and Ligand conjugates, wherein the biologically active molecule is linked to the Ligand through a linker. The disclosure further provides compositions comprising biologically active molecule -ligand conjugates, methods of modifying abnormal cell growth and methods of treatment using the conjugates or the compositions.