N-羟乙基-3,4-亚甲二氧基苯胺盐酸盐

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 中文名称: N-羟乙基-3,4-亚甲二氧基苯胺盐酸盐
• 中文别名: N-(2-羟乙基)-3,4-亚甲二氧基苯胺盐酸盐
• 英文名称: 2-(1,3-benzodioxol-5-ylamino)ethanol;hydron;chloride
• 化学式: C9H12ClNO3
• 分子量: 217.65
• InChiKey: LMONVTDNVNEAQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.24
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  50.7
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] ACRYLATE-FUNCTIONAL BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COPOLYMER FORMED THEREWITH<br/>[FR] COMPOSÉ D'ORGANOSILICIUM RAMIFIÉ À FONCTION ACRYLATE, SON PROCÉDÉ DE PRÉPARATION ET COPOLYMÈRE FORMÉ AVEC CELUI-CI
  申请人：DOW SILICONES CORP

  公开号：WO2020142474A1

  公开（公告）日：2020-07-09

  A method of preparing an acrylate-functional branched organosilicon compound ("compound") is provided, and comprises reacting (A) a branched organosilicon compound and (B) an acrylate compound in the presence of (C) a catalyst, wherein component (A) has the general formula X-Si(R1)3, where X comprises a halogen-functional moiety and each R1 is selected from R and –OSi(R4)3, with the proviso that at least one R1 is –OSi(R4)3; each R4 is selected from R, –OSi(R5)3, and –[OSiR2]mOSiR3; each R5 is selected from R, –OSi(R6)3, and –[OSiR2]mOSiR3; each R6 is selected from R and –[OSiR2]mOSiR3; each R is an independently selected hydrocarbyl group; and 0≤m≤100; with the proviso that at least one of R4, R5 and R6 is –[OSiR2]mOSiR3. The compound prepared by the method, a copolymer comprising the reaction product of the compound and a second compound, a method of forming the copolymer, and a composition comprising the copolymer are each also provided.

  提供了一种制备丙烯酸酯官能化分支有机硅化合物（“化合物”）的方法，包括在催化剂存在下，使（A）分支有机硅化合物和（B）丙烯酸酯化合物发生反应，其中组分（A）具有一般式X-Si（R1）3，其中X包括卤素官能基，每个R1从R和–OSi（R4）3中选择，但至少一个R1为–OSi（R4）3；每个R4从R、–OSi（R5）3和–[OSiR2]mOSiR3中选择；每个R5从R、–OSi（R6）3和–[OSiR2]mOSiR3中选择；每个R6从R和–[OSiR2]mOSiR3中选择；每个R是独立选择的烃基；且0≤m≤100；但至少一个R4、R5和R6为–[OSiR2]mOSiR3。还提供了通过该方法制备的化合物，包括化合物和第二化合物的反应产物的共聚物，形成共聚物的方法，以及包含共聚物的组合物。
• 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives
  申请人：Wella Aktiengesellschaft

  公开号：EP1746088A1

  公开（公告）日：2007-01-24

  The object of the present patent application are new 2-amino-5-aminomethyl-phenol derivatives of general formula (I) and colorants for oxidative dyeing of keratin fibers, particularly human hair, containing at least one 2-amino-5-aminomethyl-phenol derivative of formula (I) as dye component; wherein R1 denotes a five-membered or a six-membered heterocyclic ring, substituted or unsubstituted, or a physiologically tolerated, watersoluble salt thereof, and wherein R1 is not an unsubstituted 3-pyridinyl ring.

  本专利申请的对象是一种新的一般式（I）的2-氨基-5-氨甲基苯酚衍生物和用于氧化染色角蛋白纤维，特别是人类头发的色素，其中包含至少一种一般式（I）的2-氨基-5-氨甲基苯酚衍生物作为染料成分；其中R1表示一个取代或未取代的五元或六元杂环环，或其生理耐受性的水溶性盐，且其中R1不是未取代的3-吡啶基环。
• p-aminophenol derivative compounds and dye compositions containing same
  申请人：——

  公开号：US20010054207A1

  公开（公告）日：2001-12-27

  The p-aminophenol derivative compounds of formula (1), or their physiologically compatible water-soluble salts: 1 are useful as developer compounds in oxidation dye compositions for keratin fibers. Oxidation dye compositions for keratin fibers, including hair, and methods of dyeing hair using the p-aminophenol derivative compounds are also described.

  公式（1）中的p-氨基酚衍生物化合物，或其生理相容的水溶性盐：1在氧化染料组合物中作为角蛋白纤维的显影剂化合物是有用的。还描述了用于角蛋白纤维（包括头发）的氧化染料组合物，以及使用p-氨基酚衍生物化合物染发的方法。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。