5-{(E)-[2-(3,4-difluorophenoxy)phenyl]methylidene}-1,3-thiazolane-2,4-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-{(E)-[2-(3,4-difluorophenoxy)phenyl]methylidene}-1,3-thiazolane-2,4-dione
• 英文别名: (5E)-5-[[2-(3,4-difluorophenoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
• 化学式: C₁₆H₉F₂NO₃S
• 分子量: 333.3
• InChiKey: PSOBQTLPAISQGD-VGOFMYFVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.7
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Benzylidene-1,3-thiazolidine-2,4-dione compounds for stimulating or inducing the growth and/or for reducing the loss and/or for increasing the density of keratin fibers
  申请人：Boulle Christophe

  公开号：US20070059265A1

  公开（公告）日：2007-03-15

  The benzylidene-1,3-thiazolidine-2,4-dione compounds having the structural formula (I), or salt and/or solvate and/or isomer thereof: are useful active agents for inducing and/or stimulating the growth of mammalian keratin fibers and/or reducing the loss and/or increasing the density thereof, particularly of human head hair, beard hair, moustache hair, eyelashes and eyebrows, and advantageously are active agents for caring for or making up the hair or the eyelashes.

  苯甲醛基-1,3-噻唑啉-2,4-二酮化合物具有结构式（I），或其盐和/或溶剂和/或异构体：对于诱导和/或刺激哺乳动物角蛋白纤维的生长和/或减少其脱落和/或增加密度特别是人类头发，胡须，小胡子，睫毛和眉毛，具有有益的活性成分，可用于护理或化妆头发或睫毛。
• Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening
  申请人：Boulle Christophe

  公开号：US20070071699A1

  公开（公告）日：2007-03-29

  The benzylidene-1,3-thiazolidine-2,4-dione compounds having the structural formula (I), or salt and/or solvate and/or isomer thereof: are useful active agents for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or preventing and/or limiting the depigmentation and/or bleaching thereof, particularly of human head hair, beard hair, moustache hair, eyelashes and eyebrows, and advantageously are active agents for preventing and/or limiting the canities of human keratin fibers.

  具有结构式（I）或其盐和/或溶剂和/或异构体的苯甲醛基-1,3-噻唑啉-2,4-二酮化合物是促进和/或诱导和/或刺激角蛋白质材料的色素沉淀和/或预防和/或限制其褪色和漂白的有用活性剂，特别是人类头发、胡须、胡子、睫毛和眉毛，优点是预防和/或限制人类角蛋白质纤维的白发。