6-(4-Ethylphenyl)-2-methyl-2,3-dihydropyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-(4-Ethylphenyl)-2-methyl-2,3-dihydropyridine
• 英文别名: 6-(4-ethylphenyl)-2-methyl-2,3-dihydropyridine
• 化学式: C₁₄H₁₇N
• 分子量: 199.29
• InChiKey: KDAFEKWTCNAVHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] NOVEL USES<br/>[FR] NOUVELLES UTILISATIONS
  申请人：INTRA CELLULAR THERAPIES INC

  公开号：WO2020069043A1

  公开（公告）日：2020-04-02

  The disclosure provides the administration of inhibitors of phosphodiesterase 1 (PDE1) for the treatment and prophylaxis of diseases or disorders characterized by inflammation, including methods of treatment and pharmaceutical compositions for use therein.
• [EN] ORGANIC COMPOUNDS<br/>[FR] COMPOSÉS ORGANIQUES
  申请人：INTRA CELLULAR THERAPIES INC

  公开号：WO2020210614A1

  公开（公告）日：2020-10-15

  The present invention relates to novel compounds having a capacity for PDE1 inhibition which may be used as tracers for use in diagnostic techniques, biomarkers for phosphodiesterase 1 (PDE1) in vivo, methods for treating and/or developing novel therapies for PDE1-associated conditions, and to methods of detection and treatment.