2-(N'-fluorocarbamimidoyl)benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(N'-fluorocarbamimidoyl)benzoic acid
• 化学式: C₈H₇FN₂O₂
• 分子量: 182.15
• InChiKey: JICFSSXHBPRWFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.7
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• PROCESS FOR THE PREPARATION OF BENZOYL SUBSTITUTED BICYLIC COMPOUNDS AND CHIRAL BNEZOPYRAN DERIVATIVES
  申请人：Eli Lilly & Company

  公开号：EP1286982A2

  公开（公告）日：2003-03-05
• [EN] METHODS FOR COUPLING BENZOYL COMPOUNDS AND AMINO SUBSTITUTED BICYCLIC DERIVATIVES AND ENANTIOMERICALLY PURE OR ENRICHED COMPOSITIONS MADE THEREFROM<br/>[FR] PROCEDES DE COUPLAGE DE COMPOSES DE BENZOYLE ET DE DERIVES BICYCLIQUES AMINO SUBSTITUES, ET COMPOSITIONS ENANTIOMERIQUEMENT PURES OU ENRICHIES EN ETANT FAITES
  申请人：LILLY CO ELI

  公开号：WO2001094333A2

  公开（公告）日：2001-12-13

  Disclosed are processes for coupling amino substituted 2-chromanyl derivatives and benzoyl derivatives via an amide bond, and intermediates for producing platelet aggregation inhibitors and for producing potent platelet aggregation inhibitors. Also disclosed are processes for producing such compounds from chiral intermediates to provide desired enantiomers, and methods for using the compounds as platelet aggregation inhibitors.