tetraethyl 4'-pentyl-6-phenylselanylbiphenyl-2,3,4,5-tetracarboxylate | 1237760-39-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tetraethyl 4'-pentyl-6-phenylselanylbiphenyl-2,3,4,5-tetracarboxylate
• 英文别名: Tetraethyl 5-(4-pentylphenyl)-6-phenylselanylbenzene-1,2,3,4-tetracarboxylate；tetraethyl 5-(4-pentylphenyl)-6-phenylselanylbenzene-1,2,3,4-tetracarboxylate
• CAS: 1237760-39-2
• 化学式: C₃₅H₄₀O₈Se
• 分子量: 667.658
• InChiKey: XDHAXQWGYQJVBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.45
• 重原子数：
  44
• 可旋转键数：
  19
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  [(4-pentylphenyl)ethynyl](phenyl)selane 、 丁炔二酸二乙酯 在 bis-triphenylphosphine-palladium(II) chloride 作用下， 以 甲苯 为溶剂， 反应 16.0h， 以68%的产率得到tetraethyl 4'-pentyl-6-phenylselanylbiphenyl-2,3,4,5-tetracarboxylate
  参考文献：
  名称：

  Palladium-catalyzed alkynylselenation of acetylenedicarboxylates leading to enyne selenides and application to synthesis of multisubstituted aryl selenides

  摘要：

  Upon treatment of a mixture of alkynyl selenides and acetylenedicarboxylates with Pd(OAc)(2)/P(o-tol)(3)/K2CO3/H2O-catalytic system, the alkynylselenation of acetylenedicarboxylates takes place to give the corresponding alkynylvinyl selenides. Furthermore, alkynyl selenides undergo the intermolecular [2+2+2] cycloaddition reaction in the presence of PdCl2(PPh3)(2) as a catalyst, affording the corresponding multisubstituted aryl selenides selectively.(C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.04.125

文献信息

• Palladium-catalyzed alkynylselenation of acetylenedicarboxylates leading to enyne selenides and application to synthesis of multisubstituted aryl selenides
  作者：Takenori Mitamura、Akiya Ogawa

  DOI：10.1016/j.tetlet.2010.04.125

  日期：2010.7

  Upon treatment of a mixture of alkynyl selenides and acetylenedicarboxylates with Pd(OAc)(2)/P(o-tol)(3)/K2CO3/H2O-catalytic system, the alkynylselenation of acetylenedicarboxylates takes place to give the corresponding alkynylvinyl selenides. Furthermore, alkynyl selenides undergo the intermolecular [2+2+2] cycloaddition reaction in the presence of PdCl2(PPh3)(2) as a catalyst, affording the corresponding multisubstituted aryl selenides selectively.(C) 2010 Elsevier Ltd. All rights reserved.