(3Z)-3-[(4-phenoxyanilino)methylidene]-2-benzofuran-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3Z)-3-[(4-phenoxyanilino)methylidene]-2-benzofuran-1-one
• 化学式: C₂₁H₁₅NO₃
• 分子量: 329.3
• InChiKey: FKDRBDCNSHTDTO-ZHZULCJRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• METHODS OF IDENTIFYING NON-SPECIFIC INHIBITORS OF BIOMOLECULES
  申请人：——

  公开号：US20040234942A1

  公开（公告）日：2004-11-25

  The present invention provides methods of identifying compounds that non-specifically inhibit biological reactions. The present invention further includes kits that facilitate this identification. In addition, compilations of compounds for use in high throughput drug screening that have been evaluated by the disclosed methodology are also part of the present invention. Further, the invention provides methods for identifying a false positive compound previously identified as positive in a screening assay by measuring the activity of at least one biological activity in the presence and absence of a small molecule compound capable of inhibiting aggregate formation, e.g., digitonin.
• US6887658B2
  申请人：——

  公开号：US6887658B2

  公开（公告）日：2005-05-03