S-(2-methylpropyl) 2,2-dimethylpropanethioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: S-(2-methylpropyl) 2,2-dimethylpropanethioate
• 化学式: C₉H₁₈OS
• 分子量: 174.31
• InChiKey: VIOBOMMEVDQRAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Thioester Cationic Lipids
  申请人：Translate Bio, Inc.

  公开号：US20220008338A1

  公开（公告）日：2022-01-13

  Disclosed are cationic lipids which are compounds of Formula (I), (II), (III), (IV), (V), or (VI). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.