N-(10-nitrosoanthracen-9-yl)hydroxylamine | 7461-27-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: N-(10-nitrosoanthracen-9-yl)hydroxylamine
• 英文别名: Anthrachinon-dioxim；Anthrachinon-(9,10)-dioxim
• CAS: 7461-27-0
• 化学式: C₁₄H₁₀N₂O₂
• 分子量: 238.246
• InChiKey: RFNBPGZNARQUMR-VMNXYWKNSA-N

物化性质

• 沸点：
  457.5±41.0 °C(Predicted)
• 密度：
  1.35±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.45
• 重原子数：
  18.0
• 可旋转键数：
  0.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  65.18
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  N-(10-nitrosoanthracen-9-yl)hydroxylamine 生成 N,N'-Dinitroso-9,10-bis-hydroxylamino-anthracen
  参考文献：
  名称：

  A New Reaction of Oximes and Nitric Oxide

  摘要：

  DOI：

  10.1021/jo01067a072

文献信息

• [EN] ANTHRAQUINONE DIOXIMES AND USES THEREOF<br/>[FR] DIOXIMES D'ANTHRAQUINONE ET LEURS UTILISATIONS
  申请人：AVALON PHARMACEUTICALS

  公开号：WO2010059142A1

  公开（公告）日：2010-05-27

  Anthraquinone dioximes and their derivatives are disclosed for use in treatment of diseases, especially cancer, such as colon and colorectal cancer. Methods of preparing such derivatives are also presented. Compositions of these compounds, as well as metabolites of said compounds and their use in gene modulation are also described.

  Anthraquinone dioximes 及其衍生物被揭示用于治疗疾病，特别是癌症，如结肠和结直肠癌。还介绍了制备这些衍生物的方法。同时，还描述了这些化合物的组成，以及其代谢物和在基因调控中的使用。
• Thermoplastic compositions comprising blends of styrene-acrylonitrile resin and nitrile rubber, and a process for their production
  申请人：MONSANTO COMPANY

  公开号：EP0004776A2

  公开（公告）日：1979-10-17

  Thermoplastic compositions comprise blends of 25 to 65 parts by weight of thermoplastic SAN resin and 75 to 35 parts by weight of a nitrile rubber per 100 total parts by weight of resin and rubber, in which the rubber is present as a dispersion of particles of the rubber in a matrix of the SAN resin. the rubber having a toluene-insoluble gel content of at least 85%. Preferred compositions having both thermoplastic and elastomeric properties comprise a blend of 25 to 40 parts by weight of SAN resin and 75 to 60 parts by weight of nitrile rubber. A preferred process for the production of compositions of the invention comprises continuous mastication of a blend of SAN resin and nitrile rubber with curative for the rubber at curing temperature until the required extent of cross-linking of the rubber is attained.

  热塑性组合物包括以每 100 份树脂和橡胶总重量计，25 至 65 份热塑性 SAN 树脂和 75 至 35 份丁腈橡胶的混合物，其中橡胶以橡胶颗粒分散在 SAN 树脂基体中的形式存在，橡胶的甲苯不溶胶含量至少为 85%。具有热塑性和弹性两种特性的优选组合物包括 25 至 40 份（按重量计）SAN 树脂和 75 至 60 份（按重量计）丁腈橡胶的混合物。生产本发明组合物的优选工艺包括在硫化温度下用橡胶用硫化剂连续咀嚼 SAN 树脂和丁腈橡胶的混合物，直到橡胶达到所需的交联程度。
• Polyvinyl chloride thermoplastic elastomer composition
  申请人：DENKI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0353525B1

  公开（公告）日：1996-10-23
• US4104329A
  申请人：——

  公开号：US4104329A

  公开（公告）日：1978-08-01
• US4116914A
  申请人：——

  公开号：US4116914A

  公开（公告）日：1978-09-26