O-(2-hydroxyethyl) 2,2-dimethylpropanethioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: O-(2-hydroxyethyl) 2,2-dimethylpropanethioate
• 化学式: C₇H₁₄O₂S
• 分子量: 162.25
• InChiKey: BIARWFILZAKVMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  61.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT
  申请人：Deshpande Milind

  公开号：US20160016986A1

  公开（公告）日：2016-01-21

  5′-Deuterated nucleosides and nucleotides and modifications thereof are provided for use in medical therapies, including as antiviral, anti-tumor and anti-neoplastic agents. In one embodiment, compounds, methods and uses are provided for the treatment of hepatitis C, RSV, HSV and other viral diseases in a host, including a human.

  提供了用于医疗疗法的5'-氘代核苷和核苷酸以及其修饰，包括作为抗病毒、抗肿瘤和抗肿瘤剂。在一个实施例中，提供了化合物、方法和用途，用于治疗丙型肝炎、RSV、HSV和其他病毒性疾病在宿主中，包括人类。
• [EN] STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT<br/>[FR] NUCLÉOTIDES STABILISÉS POUR TRAITEMENT MÉDICAL
  申请人：ACHILLION PHARMACEUTICALS INC

  公开号：WO2016014527A2

  公开（公告）日：2016-01-28

  5'-Deuterated nucleosides and nucleotides and modifications thereof are provided for use in medical therapies, including as antiviral, anti-tumor and anti-neoplastic agents. In one embodiment, compounds, methods and uses are provided for the treatment of hepatitis C, RSV, HSV and other viral diseases in a host, including a human.