N1-环己基-N3-甲基-1,3-丙二胺 | 90853-13-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N1-环己基-N3-甲基-1,3-丙二胺
• 英文名称: 1-Methylamino-3-cyclohexylamino-propan
• 英文别名: N-Cyclohexyl-N'-methyl-1,3-propanediamine；N'-cyclohexyl-N-methylpropane-1,3-diamine
• CAS: 90853-13-7
• 化学式: C₁₀H₂₂N₂
• 分子量: 170.298
• InChiKey: ZVWQHCRUSNYNIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2921300090

文献信息

• [EN] HETEROCYCLIC COMPOUNDS AND USE THEREOF<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES ET UTILISATION DE CES COMPOSÉS
  申请人：NATIONAL HEALTH RES INST

  公开号：WO2018132326A1

  公开（公告）日：2018-07-19

  Heterocyclic compounds of Formula (I) shown herein. Also disclosed is a pharmaceutical composition containing one of the heterocyclic compounds. Further disclosed are methods of using one of the heterocyclic compounds for mobilizing hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation, and for treating tissue injury, cancer, inflammatory disease, and autoimmune disease.

  本文所示的式(I)的杂环化合物。还公开了含有其中一种杂环化合物的药物组合物。进一步公开了使用其中一种杂环化合物将造血干细胞和内皮祖细胞转移到外周循环，并用于治疗组织损伤、癌症、炎症性疾病和自身免疫疾病的方法。
• [EN] COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS<br/>[FR] COMPOSES ET COMPOSITIONS UTILISES COMME INHIBITEURS DE LA CATHEPSINE S
  申请人：NOVARTIS AG

  公开号：WO2006018284A1

  公开（公告）日：2006-02-23

  The present invention relates to the use of a 2-cyanopyrimidine compound of the formula (I), wherein R1, R2, R3 and X are as defined in the specification and in the claims, in free form or in salt form, and , where possible, in tautomeric form, as an inhibitor of the activity of cathepsin S.

  本发明涉及使用式(I)的2-氰基嘧啶化合物，其中R1、R2、R3和X如规范和权利要求中定义的那样，以自由形式或盐形式，并在可能的情况下以互变异构形式，作为猫hepsin S活性的抑制剂。
• Charged compounds comprising a nucleic acid binding moiety and uses therefor
  申请人：Ge Yigong

  公开号：US20070105135A1

  公开（公告）日：2007-05-10

  Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.

  提供了带有一个或多个局部正电荷区域的带电化合物，包括含有这种化合物的组合物，合成这种化合物的方法，筛选这种化合物以识别具有抗感染活性的化合物的方法，以及使用这种化合物预防或抑制感染的方法。这些化合物和含有它们的组合物具有多种应用，包括在人类和动物医学以及农业中使用。
• COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS
  申请人：Hart Terance William

  公开号：US20090048230A1

  公开（公告）日：2009-02-19

  The present invention relates to the use of a 2-cyanopyrimidine compound of the formula wherein R 1 , R 2 , R 3 and X are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in tautomeric form, as an inhibitor of the activity of cathepsin S.

  本发明涉及使用式中R1、R2、R3和X如规范和权利要求中定义的2-氰基嘧啶化合物的自由形式或盐形式及在可能的情况下互变异构体形式，作为猫hepsin S活性的抑制剂。
• ANTIPATHOGENIC BENZAMIDE COMPOUNDS
  申请人：BURLI Roland W.

  公开号：US20080200465A1

  公开（公告）日：2008-08-21

  The present invention is related to methods of treating viral and protozoan infections in mammals using antipathogenic benzamide compounds having the formula wherein at least one of the R 1 groups is F, Cl, CN or CF 3 and R 2 , R 3 , Y, Z, m, and n are as defined herein.