N,N-dibenzyl-2,6-dichloro-3-nitrosopyridin-4-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-dibenzyl-2,6-dichloro-3-nitrosopyridin-4-amine
• 化学式: C₁₉H₁₅Cl₂N₃O
• 分子量: 372.2
• InChiKey: KPPYBEBKBZHNTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
  申请人：Galapagos NV

  公开号：US20210169879A1

  公开（公告）日：2021-06-10

  The present invention discloses compounds according to Formula I: Wherein R 1 , L 1 , R 2 , L 2 , R 3 , Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNα, IL12 and/or IL23 by administering the compound of the invention.