N-Methyl-N'-[1-methyl-but-(E)-ylidene]-hydrazine | 51658-44-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Methyl-N'-[1-methyl-but-(E)-ylidene]-hydrazine
• 英文别名: 2-Pentanone, methylhydrazone；N-(pentan-2-ylideneamino)methanamine
• CAS: 51658-44-7
• 化学式: C₆H₁₄N₂
• 分子量: 114.191
• InChiKey: RXUXVCIPHMDFAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-Methyl-N'-[1-methyl-but-(E)-ylidene]-hydrazine 在 三氯化磷 作用下， 生成 4-Ethyl-2,5-dimethyl-2H-[1,2,3]diazaphosphole
  参考文献：
  名称：

  Baccolini, Graziano, Journal of the Chemical Society. Perkin transactions I, 1989, p. 1053 - 1056

  摘要：

  DOI：
• 作为产物：
  描述：

  2-戊酮 、 甲基肼 以 苯 为溶剂， 反应 3.0h， 生成 N-Methyl-N'-[1-methyl-but-(E)-ylidene]-hydrazine
  参考文献：
  名称：

  Synthesis of 2-alkenylpyrazol-3(2H)-one derivatives under mild conditions

  摘要：

  The title compounds have been synthesized by a one-pot two-stage reaction of PCI,, ketone methyl-hydrazones and methyl acetoacetate. Both stages were carried out at room temperature and the corresponding 2-alkenyl-1,5-dimethylpyrazol-3(2H)-ones 5, which are an unknown series of pyrazolones, were obtained in good yields. Use of a variety of enolizable ketones has shown that the reaction always occurs with the predominance of the (E)-isomer. X-Ray structure determinations of an (E)- and a (Z)-derivative [(E)-5c.HCl and (Z)-5b] permitted the assignment of their structures. The aromaticity of these derivatives is discussed.

  DOI：

  10.1039/p19920001729

文献信息

• Baccolini, Graziano, Journal of the Chemical Society. Perkin transactions I, 1989, p. 1053 - 1056
  作者：Baccolini, Graziano

  DOI：——

  日期：——
• Synthesis of 2-alkenylpyrazol-3(2H)-one derivatives under mild conditions
  作者：Graziano Baccolini、Daniele Evangelist、Corrado Rizzoli、Paolo Sgarabotto

  DOI：10.1039/p19920001729

  日期：——

  The title compounds have been synthesized by a one-pot two-stage reaction of PCI,, ketone methyl-hydrazones and methyl acetoacetate. Both stages were carried out at room temperature and the corresponding 2-alkenyl-1,5-dimethylpyrazol-3(2H)-ones 5, which are an unknown series of pyrazolones, were obtained in good yields. Use of a variety of enolizable ketones has shown that the reaction always occurs with the predominance of the (E)-isomer. X-Ray structure determinations of an (E)- and a (Z)-derivative [(E)-5c.HCl and (Z)-5b] permitted the assignment of their structures. The aromaticity of these derivatives is discussed.