Sulphetrone | 118-84-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Sulphetrone
• 英文别名: 1-phenyl-3-[4-[4-[(3-phenyl-1,3-disulfopropyl)amino]phenyl]sulfonylanilino]propane-1,3-disulfonic acid
• CAS: 118-84-3
• 化学式: C₃₀H₃₂N₂O₁₄S₅
• 分子量: 804.9
• InChiKey: HCCUQCPVNVAHMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  51
• 可旋转键数：
  16
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  318
• 氢给体数：
  6
• 氢受体数：
  16

文献信息

• COMPOSITIONS CONTAINING SUBSTITUTED QUINOLINES AND SUBSTITUTED DIPHENYL SULFONES AND METHODS OF USE
  申请人：Giulian J. Dana

  公开号：US20070129439A1

  公开（公告）日：2007-06-07

  Combination therapies of substituted quinolines and substituted diphenyl sulfones are disclosed. More specifically, compositions containing substituted quinolines and substituted diphenyl sulfones are disclosed. In addition, methods of using the compositions in the treatment of neurodegenerative disorders, including, inter alia, Alzheimer's dementia, HIV-1 associated dementia, and Creutzfeld-Jakob disease are also disclosed.