O-苯基1H-咪唑-1-硫代甲酸酯 | 90842-16-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: O-苯基1H-咪唑-1-硫代甲酸酯
• 英文名称: Imidazol-thiocarbonsaeure-(1)-O-phenylester
• 英文别名: imidazole-1-carbothioic acid O-phenyl ester；O-phenyl 1H-imidazole-1-carbothioate；O-phenyl imidazole-1-carbothioate
• CAS: 90842-16-3
• 化学式: C₁₀H₈N₂OS
• 分子量: 204.252
• InChiKey: KSEUJDGVAVFITI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Pharmaceutical preparations comprising a COS releasing compound
  申请人：Universität Wien

  公开号：EP2343063A1

  公开（公告）日：2011-07-13

  The present invention relates to pharmaceutical compositions comprising a COS releasing compound and to methods of preparing such compositions. Said pharmaceutical compositions may preferably be used for the treatment and/or the prevention of cardiovascular diseases.

  本发明涉及包含 COS 释放化合物的药物组合物以及制备此类组合物的方法。所述药物组合物最好可用于治疗和/或预防心血管疾病。
• PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND
  申请人：Erker Thomas

  公开号：US20130005739A1

  公开（公告）日：2013-01-03

  The present invention relates to pharmaceutical compositions comprising a COS releasing compound according to formula (I) and to methods of preparing such compositions. Said pharmaceutical compositions may preferably be used for the treatment and/or the prevention of cardiovascular diseases.
• [EN] PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND<br/>[FR] PRÉPARATIONS PHARMACEUTIQUES COMPRENANT UN COMPOSÉ DE LIBÉRATION DE COS
  申请人：UNIV WIEN

  公开号：WO2011080269A2

  公开（公告）日：2011-07-07

  The present invention relates to pharmaceutical compositions comprising a COS releasing compound according to formula (I) and to methods of preparing such compositions. Said pharmaceutical compositions may preferably be used for the treatment and/or the prevention of cardiovascular diseases.