Formaldehyde;phenoxybenzene | 26007-63-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Formaldehyde;phenoxybenzene
• CAS: 26007-63-6
• 化学式: C13H12O2
• 分子量: 200.23
• InChiKey: JBVCEGLZIMVTFE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.29
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOSITION COMPRISING TETRACYCLIC COMPOUND
  申请人：Furumoto Kentaro

  公开号：US20130143877A1

  公开（公告）日：2013-06-06

  A composition which comprises substance represented by Formula (I), [Meanings of the symbols that are included in the formula are given in the specification as definitions] a pharmaceutically acceptable carrier, and a dissolution aid. is useful for improving solubility, oral absorbability and/or absorbability in blood of a poorly water-soluble or water insoluble tetracyclic compounds having an ALK inhibitory activity that are useful as a prophylactic and/or therapeutic agent for cancer, depression, and cognitive function disorder.

  由公式（I）代表的物质，药用可接受的载体和溶解助剂组成的组合物，可用于改善具有ALK抑制活性的水溶性差或水不溶的四环化合物的溶解度、口服吸收性和/或血液吸收性，这些化合物可用作癌症、抑郁症和认知功能障碍的预防和/或治疗药物。
• AGRICULTURAL-CHEMICAL PREPARATION HAVING CONTROLLED RELEASABILITY
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1774853A1

  公开（公告）日：2007-04-18

  An object of the present invention is to provide an agricultural chemical formulation which is able to control release of an agricultural chemical active ingredient. This agricultural chemical formulation includes a composition, containing an agricultural chemical active ingredient, styrene-maleic anhydride copolymer or mixture of styrene-maleic anhydride copolymer and polymer having repeating units derived from rosin or derivative thereof or salicylic acid or derivative thereof, and a release controller (a water-soluble polymer, a hydrophobically-treated silicon oxide, or a surfactant), forming a compatible state or matrix.

  本发明的目的是提供一种能够控制农业化学活性成分释放的农业化学制剂。这种农用化学制剂包括一种组合物，其中含有农用化学活性成分、苯乙烯-马来酸酐共聚物或苯乙烯-马来酸酐共聚物与具有来自松香或其衍生物或水杨酸或其衍生物的重复单元的聚合物的混合物，以及释放控制剂（水溶性聚合物、疏水处理的氧化硅或表面活性剂），形成一种相容状态或基质。
• GLYCYRRHIZIN-CONTAINING SUPPOSITORY COMPOSITIONS FOR RECTAL INFUSION
  申请人：Minophagen Pharmaceutical Co., Ltd.

  公开号：EP1779854A1

  公开（公告）日：2007-05-02

  The present invention provides a glycyrrhizin-containing suppository composition for rectal infusion which contains: at least one selected from glycyrrhizin and pharmaceutically acceptable salts thereof; a nonionic surfactant; an oily base; and water, the glycyrrhizin-containing suppository composition for rectal infusion having a (solid-liquid) phase transition point of 10 to 4500 Pa at 37°C. Also, the present invention provides a glycyrrhizin-containing suppository composition for rectal infusion which contains: at least one selected from glycyrrhizin and pharmaceutically acceptable salts thereof; an oily base; water; and an alkali.

  本发明提供了一种用于直肠输液的含甘草酸苷栓剂组合物，该组合物含有：至少一种选自甘草酸苷及其药学上可接受的盐；一种非离子表面活性剂；一种油性基质；以及水，该用于直肠输液的含甘草酸苷栓剂组合物在37℃时的（固-液）相变点为10至4500Pa。 此外，本发明还提供了一种用于直肠灌注的含甘草苷栓剂组合物，它包含：至少一种选自甘草苷及其药学上可接受的盐；油性碱；水；和碱。
• PESTICIDE-CONTAINING RESIN COMPOSITIONS CONTROLLED IN DISSOLUTION, PROCESS FOR PRODUCTION THEREOF, AND PESTICIDE PREPARATIONS
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1982590A1

  公开（公告）日：2008-10-22

  A resin composition containing an agricultural chemical in which the release of an agricultural chemical active ingredient is controlled; a production method thereof; and an agricultural chemical formulation; in other words, an agricultural chemical-containing resin composition which is a composition containing an agricultural chemical active ingredient, a resin, and a fatty acid metal salt, and characterized in that the composition is either in a compatible state or forming a matrix; its production method; and an agricultural chemical formulation including at least one of the agricultural chemical-containing resin compositions; in addition to an agricultural chemical-containing resin composition which is a composition containing an agricultural chemical active ingredient, a (meth)acrylate based resin, and a release controlling agent, and characterized in that the composition is either in a compatible state or forming a matrix; its production method; and an agricultural chemical formulation including at least one of the agricultural chemical-containing resin compositions, are provided.

  一种含有农业化学活性成分的树脂组合物，其中农业化学活性成分的释放受到控制；其生产方法；以及一种农业化学制剂；换句话说，一种含有农业化学活性成分的树脂组合物，它是一种含有农业化学活性成分、树脂和脂肪酸金属盐的组合物，其特征在于该组合物处于相容状态或形成基质；其生产方法；此外，还提供了一种含农用化学品的树脂组合物，该组合物是一种含有农用化学品活性成分、（甲基）丙烯酸酯基树脂和释放控制剂的组合物，其特征在于该组合物处于相容状态或形成基质；其生产方法；以及一种含有至少一种含农用化学品的树脂组合物的农用化学品制剂。
• COMPOSITION CONTAINING TETRACYCLIC COMPOUND
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：EP2606886A1

  公开（公告）日：2013-06-26

  A composition which comprises substance represented by Formula (I), [Meanings of the symbols that are included in the formula are given in the specification as definitions] a pharmaceutically acceptable carrier, and a dissolution aid.is useful for improving solubility, oral absorbability and/or absorbability in blood of a poorly water-soluble or water insoluble tetracyclic compounds having an ALK inhibitory activity that are useful as a prophylactic and/or therapeutic agent for cancer, depression, and cognitive function disorder.

  一种由式 (I) 所代表的物质组成的组合物、 式（I）代表的物质，[式（I）中包含的符号的含义在说明书中作为定义给出]。 用于改善具有 ALK 抑制活性的水溶性差或不溶于水的四环化合物的溶解度、口服可吸收性和/或血液可吸收性，该化合物可用作癌症、抑郁症和认知功能障碍的预防剂和/或治疗剂。