1-methyl-4-t-butylpyridinyl radical | 33255-76-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-methyl-4-t-butylpyridinyl radical
• 英文别名: 4-Tert-butyl-1-methylpyridin-1-ium
• CAS: 33255-76-4
• 化学式: C₁₀H₁₆N
• 分子量: 150.244
• InChiKey: DJUQOTYUKCLFSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Chromonic nanoparticles containing bioactive compounds
  申请人：Mohanty Sanat

  公开号：US20070086965A1

  公开（公告）日：2007-04-19

  A chromonic nanoparticle mixture prepared by combining (i) a continuous water-soluble polymer phase and (ii) a discontinuous chromonic phase comprising a chromonic material; and non-covalently crosslinking the resulting chromonic nanoparticles with a polyvalent cation salt.

  通过将（i）连续的水溶性聚合物相和（ii）包含色相材料的不连续色相相结合制备的色相纳米颗粒混合物；并且用多价阳离子盐非共价交联所得的色相纳米颗粒。
• CCR2 INHIBITORS AND METHODS OF USE THEREOF
  申请人：Basak Arindrajit

  公开号：US20100234364A1

  公开（公告）日：2010-09-16

  Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists, and as controls in assays for the identification of CCR9 antagonists.

  提供了作为CCR2或CCR9受体强效拮抗剂的化合物。动物实验表明，这些化合物对于治疗炎症非常有效，而炎症是CCR2和CCR9的典型疾病。这些化合物通常是芳基磺酰胺衍生物，在制药组合物、治疗CCR2介导疾病的方法、治疗CCR9介导疾病的方法、作为CCR2拮抗剂鉴定的检测中的对照物，以及作为CCR9拮抗剂鉴定的检测中的对照物中非常有用。
• VOLTAGE-SENSITIVE DYE AND METHOD OF PREPARING THE SAME
  申请人：BAEK Nam Seob

  公开号：US20110144348A1

  公开（公告）日：2011-06-16

  Provided is a voltage sensitive dye represented by Formula 7. Through connection of an electron donor with an electron acceptor by a triple bond, the voltage sensitive dye has a lower free rotation rate in molecular structures of the electron donor and the electron acceptor (e.g., photoisomerization), and thus fluorescence efficiency and voltage sensitivity to external electron stimulation can be improved.

  提供的是由第7式表示的电压敏感染料。通过通过三键将电子给体与电子受体连接起来，电压敏感染料在电子给体和电子受体的分子结构中具有较低的自由旋转速率（例如，光异构化），从而可以提高荧光效率和对外部电子刺激的电压敏感性。
• CATALYSTS AND METHODS FOR POLYMER SYNTHESIS
  申请人：NOVOMER, INC.

  公开号：US20130144032A1

  公开（公告）日：2013-06-06

  The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

  本发明提供了在二氧化碳和环氧化物的共聚合中具有增强活性的单分子金属配合物。还提供了使用这种金属配合物在合成聚合物中的方法。根据一个方面，本发明提供了包括与具有共催化活性的活化物种相耦合的多齿配体的金属配合物，该多齿配体与复合物的活性金属中心配位。
• Method and Apparatus for Forming Chromonic Nanoparticles
  申请人：Tokie H. Jeffrey

  公开号：US20070128291A1

  公开（公告）日：2007-06-07

  A method and apparatus for forming guest molecules encapsulated with chromonic material are described. The method includes atomizing a solution to form a pre-atomized particle stream. The solution includes chromonic material, a guest molecule and a carrier fluid. Then, atomizing the pre-atomized particle stream to form an atomized particle stream; evaporating at least a portion of the carrier fluid from the atomized particle stream to form a dried atomized particle stream, and forming encapsulated guest molecules from the dried atomized particle stream.

  本发明涉及一种形成以色素物质封装的客体分子的方法和装置。该方法包括将溶液雾化以形成预雾化的颗粒流。该溶液包括色素物质、客体分子和载体流体。然后，将预雾化的颗粒流雾化以形成雾化的颗粒流；从雾化的颗粒流中蒸发至少一部分载体流体以形成干燥的雾化颗粒流，并从干燥的雾化颗粒流中形成封装的客体分子。