S-(2-二甲基氨乙基)异硫脲二盐酸盐 | 16111-27-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 异硫脲类
• 中文名称: S-(2-二甲基氨乙基)异硫脲二盐酸盐
• 中文别名: S-(2-二甲基氨基乙基)-5-巯基四唑；S-[2-(二甲氨基)乙基]异硫脲二盐酸盐
• 英文名称: 2-[Amino(azaniumylidene)methyl]sulfanylethyl-dimethylazanium;dichloride
• 英文别名: 2-[amino(azaniumylidene)methyl]sulfanylethyl-dimethylazanium;dichloride
• CAS: 16111-27-6
• 化学式: C5H15Cl2N3S
• mdl: MFCD00060161
• 分子量: 220.16
• InChiKey: FXBRVWUWVBAZKC-UHFFFAOYSA-N

物化性质

• 熔点：
  181°C
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  0.17
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  78.4
• 氢给体数：
  4
• 氢受体数：
  3

安全信息

• 危险类别码：
  R36/37/38
• RTECS号：
  UM3770000
• 海关编码：
  2930909090

文献信息

• Gram-positive carbapenem antibacterials and processes for their preparation
  申请人：Choi Woo-Baeg

  公开号：US20060074070A1

  公开（公告）日：2006-04-06

  The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

  本发明提供了β-甲基碳青霉烯化合物和制药组合物，可用于治疗细菌感染，并提供了使用这些化合物和/或组合物治疗此类感染的方法。本发明包括向需要此类治疗的宿主施用β-碳青霉烯化合物或盐和/或前药的有效量。本发明还属于合成有机化学领域，特别提供了一种改进的β-甲基碳青霉烯合成方法，其可用作抗菌剂。
• GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION
  申请人：Choi Woo-Baeg

  公开号：US20100075945A1

  公开（公告）日：2010-03-25

  The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

  本发明提供了β-甲基碳青霉烯化合物和制药组合物，可用于治疗细菌感染，并提供使用这些化合物和/或组合物治疗此类感染的方法。本发明包括向需要此类治疗的宿主投与有效量的碳青霉烯化合物或盐和/或前药。本发明还属于合成有机化学领域，特别提供了一种改进的β-甲基碳青霉烯化合物合成方法，该方法可用作抗菌剂。
• EP1765821A4
  申请人：——

  公开号：EP1765821A4

  公开（公告）日：2009-05-20
• COMPOSITION FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT TRANSMISSIVITY AND USE OF COMPOSITION
  申请人：RIKEN

  公开号：US20190086302A1

  公开（公告）日：2019-03-21

  The present invention relates to a clearing technique which uses a solution containing at least one of a compound having a delipidation ability, a compound having a biochrome decoloring ability, a compound having a decalcification ability, a compound having a refractive index adjusting ability, and a compound having a tissue swelling ability. The clearing technique is suitable for use in high-throughput and low-magnification imaging which involves a simple process.
• US7632828B2
  申请人：——

  公开号：US7632828B2

  公开（公告）日：2009-12-15

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