Paraquat methosulfate | 2074-50-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Paraquat methosulfate
• 英文别名: 1-methyl-4-(1-methylpyridin-1-ium-4-yl)pyridin-1-ium;methyl sulfate
• CAS: 2074-50-2
• 化学式: C14H20N2O8S2
• 分子量: 408.5
• InChiKey: WXJYKXOIFICRPR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -0.81
• 重原子数：
  26
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  157
• 氢给体数：
  0
• 氢受体数：
  8

ADMET

毒理性

• 副作用

职业性肝毒素 - 第二性肝毒素：在职业环境中的毒性效应潜力是基于人类摄入或动物实验的中毒案例。 肾毒素 - 该化学物质在职业环境中可能对肾脏有毒。 皮肤毒素 - 皮肤烧伤。 毒性肺炎 - 由吸入金属烟雾或有毒气体和蒸气引起的肺部炎症。 纤维原性 - 引发组织损伤和纤维化（疤痕）。 ACGIH致癌物 - 无法分类。

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting. Dermatotoxin - Skin burns. Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors. Fibrogenic - Inducing tissue injury and fibrosis (scarring). ACGIH Carcinogen - Not Classifiable.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

文献信息

• HERBICIDAL COMPOSITIONS
  申请人：Bayer Aktiengesellschaft

  公开号：US20220053762A1

  公开（公告）日：2022-02-24

  The present invention provides compositions comprising herbicidally active compounds (A) and (B), where (A) represents one or more compounds of the general formula (I) or agrochemically compatible salts thereof [component (A)], and (B) represents one or more herbicides [component (B)]. The application further relates to a method and to the use of the herbicidal composition according to the invention for controlling harmful plants or for regulating growth.

  本发明提供了包含除草活性化合物（A）和（B）的组合物，其中（A）代表通式（I）的一个或多个化合物或其农药兼容盐[组分（A）]，（B）代表一个或多个除草剂[组分（B）]。该申请进一步涉及一种方法和利用本发明的除草组合物来控制有害植物或调节生长。
• Method of formulating herbicidal compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0276911A2

  公开（公告）日：1988-08-03

  A process of preparing a herbicidal emulsion comprising 75 grams per litre or more of a salt of a herbicidal bipyridylium diquaternary cation as an active ingredient comprising as a first step agitating an aqueous solution of a herbicidal bipyridylium diquaternary salt with an oil and a first emulsifier having a low HLB value to give a first emulsion comprising droplets of herbicidal bipyridylium diquaternary salt solution dispersed in a continuous oil phase, and as a second step, agitating the first emulsion with water and a second emulsifier having a high HLB value, to give a second emulsion comprising drops of the first emulsion dispersed in a continuous aqueous phase. The emulsions have a lower oral toxicity than conventional aqueous formulations.

  一种除草乳剂的制备方法，其活性成分为每公升含 75 克或更多的除草双季铵阳离子盐，其 第一步包括用油和具有低 HLB 值的第一乳化剂搅拌除草双季铵盐的水溶液，以得到第一乳剂， 该乳剂由分散在连续油相中的除草双季铵盐液滴组成、第二步，用水和高 HLB 值的第二乳化剂搅拌第一乳液，得到由分散在连续水相中的第一乳液液滴组成的第二乳液。与传统的水性制剂相比，乳剂的口服毒性更低。
• HERBIZIDE ZUSAMMENSETZUNGEN
  申请人：Bayer Aktiengesellschaft

  公开号：EP3890488A1

  公开（公告）日：2021-10-13
• JPH00413603A
  申请人：——

  公开号：JPH00413603A

  公开（公告）日：1992-01-17
• JPH0413603A
  申请人：——

  公开号：JPH0413603A

  公开（公告）日：1992-01-17