[4-(2,4-diamino-5-methylphenyl)iminocyclohexa-2,5-dien-1-ylidene]-dimethylazanium;chloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-(2,4-diamino-5-methylphenyl)iminocyclohexa-2,5-dien-1-ylidene]-dimethylazanium;chloride
• 化学式: C15H19ClN4
• 分子量: 290.79
• InChiKey: SRAVWPVICTXESG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.92
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• METHOD OF INHIBITING OXIDATION, WATER CAPABLE OF INHIBITING OXIDATION AND USE THEREOF
  申请人：MIZ Co., Ltd.

  公开号：EP1550637A1

  公开（公告）日：2005-07-06

  The objective of the present invention is to provide an antioxidation method and antioxidant-functioning water that can anticipate high benchmarks of safety on the antioxidation subject such as the human body and reduced environmental burden. An antioxidation method and antioxidant- functioning water that can transform or maintain an antioxidation subject, which is in an oxidation state due to a deficiency of electrons or needs to be protected from oxidation, into a reduced state where electrons are filled by promoting the breaking reaction of molecular hydrogen used as a substrate included in the hydrogen- dissolved water into a product of active hydrogen through a process employing a catalyst, which is a precious metal colloid or a hydrogen oxidation/ reduction enzyme (except for those already existing in a living organism), on the hydrogen-dissolved water.

  本发明的目的是提供一种抗氧化方法和抗氧化功能水，可以预测抗氧化主体（如人体）的高安全标准，并减少环境负担。一种抗氧化方法和抗氧化功能水，可以将处于氧化状态的抗氧化主体（由于电子不足或需要保护免受氧化）转化或维持在还原状态，通过使用催化剂（贵金属胶体或氢氧化还原酶（除已存在于生物体内的酶））在氢溶解水中，促进分子氢的断裂反应，将其转化为活性氢产物。
• Temperature indicating device and composition for use therein
  申请人：PyMaH Corporation

  公开号：EP0684463A1

  公开（公告）日：1995-11-29

  A composition for use in a reversible thermometer comprising a thermally responsive material capable of being supercooled for several minutes, and of changing state from solid to liquid at a predetermined temperature, means for visually observing the change in state, and a matrix forming material in which the thermally responsive material is dispersed, the matrix material comprising an amorphous organic compound, and being insoluble in the thermally responsive material. A suitable matrix material is polyisobutylene, and a suitable thermally responsive material is a solid solution of ortho-chloronitrobenzene and ortho-bromonitrobenzene.

  一种用于可逆温度计的组合物，包括一种能过冷几分钟并能在预定温度下从固态变为液态的热敏材料，目视观察状态变化的装置，以及一种分散热敏材料的基质形成材料，基质材料包括一种无定形有机化合物，不溶于热敏材料。一种合适的基质材料是聚异丁烯，一种合适的热敏材料是邻氯硝基苯和邻溴硝基苯的固溶体。
• METHOD OF PHOTOREDUCTION OF HEMOGLOBIN VESICLES
  申请人：JAPAN SCIENCE AND TECHNOLOGY CORPORATION

  公开号：EP1297843A1

  公开（公告）日：2003-04-02

  Disclosed is a method and apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method comprises adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.

  本发明公开了一种通过光照射还原血红蛋白-囊泡中所含的高铁血红蛋白来再生氧结合能力的方法和装置。该方法包括在血红蛋白-囊泡的内部水相中加入适量的电子供体，如氨基酸、糖类、醇类和/或黄素衍生物，当血红蛋白氧化导致高铁血红蛋白含量增加时，对囊泡进行光照，从而减少高铁血红蛋白。这样，氧结合能力就得到了恢复，从而保持了血红蛋白囊的功能。
• Photoreduction method for hemoglobin-visicle
  申请人：Japan Science and Technology Corporation

  公开号：US20020095108A1

  公开（公告）日：2002-07-18

  Disclosed is a method and apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method comprises adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.

  本发明公开了一种通过光照射还原血红蛋白-囊泡中所含的高铁血红蛋白来再生氧结合能力的方法和装置。该方法包括在血红蛋白-囊泡的内部水相中加入适量的电子供体，如氨基酸、糖类、醇类和/或黄素衍生物，当血红蛋白氧化导致高铁血红蛋白含量增加时，对囊泡进行光照，从而减少高铁血红蛋白。这样，氧结合能力就得到了恢复，从而保持了血红蛋白囊的功能。
• Method for detecting and killing epithelial cancer cells
  申请人：——

  公开号：US20030017158A1

  公开（公告）日：2003-01-23

  A diagnostic method for detecting cancerous epithelial cells by selectively marking the mitochondria of the cancer cells, by delivering to the epithelium a cationic supravital mitochondrial marking agent. Selective killing of cancerous epithelial cells in the presence of normal cells is effected by delivering a cationic supravital mitochondrial marking agent to epithelial cancer cells. The killing agent can also comprise the reaction product of the marking agent and a cancer chemotherapeutic drug or in admixture

  一种诊断方法，通过向上皮细胞输送阳离子超活力线粒体标记剂，选择性地标记癌细胞的线粒体，从而检测癌变的上皮细胞。通过向上皮癌细胞输送阳离子超活力线粒体标记剂，在正常细胞存在的情况下选择性杀死上皮癌细胞。杀灭剂还可包括标记剂和癌症化疗药物的反应产物或混合产物。

表征谱图