Disodium;5,8-bis(4-methyl-2-sulfoanilino)-9,10-dioxoanthracene-1,4-diolate

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: Disodium;5,8-bis(4-methyl-2-sulfoanilino)-9,10-dioxoanthracene-1,4-diolate
• 英文别名: disodium;5,8-bis(4-methyl-2-sulfoanilino)-9,10-dioxoanthracene-1,4-diolate
• 化学式: C28H20N2Na2O10S2
• 分子量: 654.6
• InChiKey: LERIXBKRKBHLHG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -2.21
• 重原子数：
  44
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  230
• 氢给体数：
  4
• 氢受体数：
  12

文献信息

• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0525073A1

  公开（公告）日：1993-02-03
• Methods for coating and impregnating medical devices with antiseptic compositions
  申请人：Raad Issam

  公开号：US20050197634A1

  公开（公告）日：2005-09-08

  The present invention provides methods of coating or impregnating medical devices with an antiseptic composition that will inhibit or prevent the nosocomial infections typically associated with the use of such medical devices. The present invention further provides methods of coating or impregnating medical devices that produce devices with effective activity against infection, while avoiding destroying the devices or causing the devices to become toxic. In addition, the invention provides medical devices coated or impregnated with antiseptic compositions by the aforementioned novel methods.
• METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS
  申请人：RAAD ISSAM

  公开号：US20070154621A1

  公开（公告）日：2007-07-05

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.
• MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY
  申请人：Raad Issam

  公开号：US20080183152A1

  公开（公告）日：2008-07-31

  The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.