S-(4-ethoxy-2-nitrophenyl)thiohydroxylamine | 328022-45-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-(4-ethoxy-2-nitrophenyl)thiohydroxylamine
• CAS: 328022-45-3
• 化学式: C8H10N2O3S
• mdl: MFCD00990989
• 分子量: 214.24
• InChiKey: KVVIODCAYJARDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  106
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF
  申请人：Tsai Li-Huei

  公开号：US20130096129A1

  公开（公告）日：2013-04-18

  The present invention provides compounds of Formulae (A), (B), (C), and (D), pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof, pharmaceutical compositions thereof, and kits thereof. The present invention further provides methods of using the compounds to treat or prevent neurological disorders. In one aspect, the methods include administering to a subject in need of treatment for a neurological disorder a therapeutically effective amount of DAC-001, DAC-002, DAC-003, DAC-009, or DAC-012, or a compound of Formula (A), (B), (C), or (D).
• US9115053B2
  申请人：——

  公开号：US9115053B2

  公开（公告）日：2015-08-25