Benztropine mesilate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benztropine mesilate
• 英文别名: (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;methanesulfonic acid
• 化学式: C22H29NO4S
• 分子量: 403.5
• InChiKey: CPFJLLXFNPCTDW-STYNFMPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.92
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  75.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• SOLID FORMULATIONS OF CRYSTALLINE COMPOUNDS
  申请人：Thommes Markus

  公开号：US20100222311A1

  公开（公告）日：2010-09-02

  Described herein are formulations of active pharmaceutical ingredients, where the active pharmaceutical ingredients or drugs are included in a solid suspension with one or more solid additives. The formulations described herein are useful for formulating any drug or active pharmaceutical ingredient, including those that have limited solubility in organic and/or aqueous solvent systems.
• US7790905B2
  申请人：——

  公开号：US7790905B2

  公开（公告）日：2010-09-07
• US7927613B2
  申请人：——

  公开号：US7927613B2

  公开（公告）日：2011-04-19
• [EN] COMPOSITIONS AND METHODS OF PROMOTING MYELINATION<br/>[FR] COMPOSITIONS ET MÉTHODES POUR FAVORISER LA MYÉLINISATION
  申请人：CHILDRENS MEDICAL CT CORP

  公开号：WO2021222507A1

  公开（公告）日：2021-11-04

  The invention features methods and compositions that are useful for the treatment of diseases, disorders, conditions, or injuries characterized by insufficient myelination. The methods involve administering GPR17 antagonists and microglia inhibitors or ablation agents.