1-Pyrrolidinecarboxylic acid, 2,4-dichlorophenyl ester | 40575-34-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-Pyrrolidinecarboxylic acid, 2,4-dichlorophenyl ester
• 英文别名: (2,4-dichlorophenyl) pyrrolidine-1-carboxylate
• CAS: 40575-34-6
• 化学式: C₁₁H₁₁Cl₂NO₂
• 分子量: 260.11
• InChiKey: WKMRIBJBDSRIMJ-UHFFFAOYSA-N

物化性质

• 沸点：
  358.2±42.0 °C(Predicted)
• 密度：
  1.392±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

制备方法与用途

类别：农药
毒性分级：中毒
急性毒性：口服-大鼠 LD50: 2200 毫克/公斤
可燃性危险特性：燃烧时产生有毒氯化物和氮氧化物气体
储运特性：应存放在通风、低温和干燥的库房中，并与食品原料分开储存和运输
灭火剂：干粉、泡沫或砂土

文献信息

• Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds
  申请人：KURARAY CO., LTD.

  公开号：EP0065372A1

  公开（公告）日：1982-11-24

  Substituted phenyl (thiono) carbamates capable of effectively controlling broad-leaved annual weeds and annual weeds belonging to the families Gramineae and Cyperaceae such as wild Echinochloa species, monochoria, toothcup and umbrella plant, herbicidal compositions containing these (thiono) carbamates as active ingredient and a method of controlling weeds using these (thiono) carbamates. The (thiono) carbamates are substantially non-phytotoxic to useful crop plants such as the paddy rice plant. These (thiono) carbamates have the general formula wherein X is an oxygen or sulfur atom or a vinylene group, 1 and m are each an integer of 1 to 4, n is an integer of 0 or 1, the heterocycle comprising the nitrogen atom, the two alkylene chains and X is 5- to 7-membered, the two alkylene chains may each be branched, Y is a halogen atom, p is an integer of 1 or 2, RI is a hydrogen atom or a lower alkyl group, R2 and R3 are the same or different and each is a hydrogen atom or a lower alkyl or phenyl group, R4 and R5 are the same or different and each is a halogen atom, and Z is an oxygen or sulfur atom.

  能够有效控制阔叶一年生杂草和属于禾本科和香蒲科的一年生杂草（如野生越橘、单子叶、齿颊草和伞形科植物）的取代苯基（硫代）氨基甲酸酯类化合物、含有这些（硫代）氨基甲酸酯类化合物作为活性成分的除草组合物以及使用这些（硫代）氨基甲酸酯类化合物控制杂草的方法。这些（硫代）氨基甲酸酯对有用的作物植物（如水稻）基本上没有植物毒性。 这些（硫代）氨基甲酸酯的通式为 其中 X 是氧原子、硫原子或乙烯基，1 和 m 分别是 1 至 4 的整数，n 是 0 或 1 的整数，由氮原子、两条亚烷基链和 X 组成的杂环是 5 至 7 元的，两条亚烷基链可以是支链，Y 是卤素原子、p 是 1 或 2 的整数，RI 是氢原子或低级烷基，R2 和 R3 相同或不同且各自是氢原子或低级烷基或苯基，R4 和 R5 相同或不同且各自是卤素原子，Z 是氧原子或硫原子。
• Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as acive ingredient and method of controlling weeds
  申请人：KURARAY CO., LTD.

  公开号：EP0078099A2

  公开（公告）日：1983-05-04

  The invention provides a compound of the general formula wherein X is an oxygen or sulfur atom or a vinylene group, each of ℓ and m is an integer of 1 to 4, n is 0 or 1, the heterocycle comprising the nitrogen atom, the two alkylene chains and X is 5- or 7-membered, the two alkylene chains each may be branched, Y1 is a halogen atom, Y2 is a hydrogen or halogen atom, R is an alkyl group, which may be interrupted by one or more oxygen atoms, or an optionally halo-substituted alkenyl or alkynyl group and Z is an oxygen or sulfur atom. The invention also provides herbicidal compositions containing (thiono)carbamates of the above formula as active ingredient and a method of controlling weeds using these (thiono)carbamates. The phenyl (thiono) carbamates are capable of effectively controlling broad-leaved annual weeds and annual weeds belonging to the families Gramineae and Cyperaceae such as wild Echinochloa species, monochoria, toothcup and umbrella plant. The (thiono)carbamates are substantially nonphytotoxic to useful crop plants such as the paddy rice plant.

  本发明提供了通式如下的化合物 其中X是氧原子、硫原子或乙烯基，ℓ和m各为1～4的整数，n为0或1，由氮原子、两条亚烷基链和X组成的杂环为5或7元，两条亚烷基链可以是支链、Y1 是卤素原子，Y2 是氢原子或卤素原子，R 是烷基，可被一个或多个氧原子或任选卤代的烯基或炔基打断，Z 是氧原子或硫原子。本发明还提供了含有上式（硫代）氨基甲酸酯作为活性成分的除草组合物，以及使用这些（硫代）氨基甲酸酯控制杂草的方法。苯基（硫代）氨基甲酸酯类化合物能有效防除一年生阔叶杂草和禾本科、莎草科一年生杂草，如野生越橘、单子叶、齿颊草和伞形科杂草。(硫代)氨基甲酸酯对水稻等有用的作物植物基本无植物毒性。
• Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variant thereof
  申请人：FarmHannong Co., Ltd.

  公开号：US10844395B2

  公开（公告）日：2020-11-24

  Provided is technology for conferring enhanced herbicide tolerance and/or enhancing herbicide tolerance of plants and/or algae using a protoporphyrinogen oxidase derived from prokaryotes or its amino acid variants.

  本发明提供了利用源自原核生物的原卟啉原氧化酶或其氨基酸变体赋予植物和/或藻类更强的除草剂耐受性和/或增强其除草剂耐受性的技术。
• Composition and method for conferring and/or enhancing herbicide tolerance using variants of protoporphyrinogen IX oxidase from cyanobacteria
  申请人：FarmHannong Co., Ltd.

  公开号：US11219221B2

  公开（公告）日：2022-01-11

  Provided is a technology for conferring enhanced tolerance and/or enhancing tolerance to a herbicide of a plant and/or algae by using amino acid variants of protoporphyrinogen IX oxidase derived from prokaryotes.

  本发明提供了一种利用源自原核生物的原卟啉原 IX 氧化酶氨基酸变体赋予植物和/或藻类对除草剂更强耐受性和/或增强耐受性的技术。
• Protoporphyrinogen oxidase variants and methods and compositions for conferring and/or enhancing herbicide tolerance using the same
  申请人：FarmHannong Co., Ltd.

  公开号：US11339404B2

  公开（公告）日：2022-05-24

  Provided is technology for conferring enhanced tolerance and/or enhancing tolerance to herbicide of a plant and/or algae using amino acid variants of protoporphyrinogen oxidase derived from prokaryotes.

  本发明提供了利用源自原核生物的原卟啉原氧化酶的氨基酸变体赋予植物和/或藻类更强的耐受性和/或提高其对除草剂的耐受性的技术。