(+/-)-Deprenyl hydrochloride | 2079-54-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (+/-)-Deprenyl hydrochloride
• 英文别名: Methyl-(1-phenylpropan-2-yl)-prop-2-ynylazanium;chloride；methyl-(1-phenylpropan-2-yl)-prop-2-ynylazanium;chloride
• CAS: 2079-54-1
• 化学式: C₁₃H₁₇N*ClH
• mdl: MFCD00055150
• 分子量: 223.746
• InChiKey: IYETZZCWLLUHIJ-UHFFFAOYSA-N

物化性质

• 溶解度：
  18.4 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  2.85
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.384
• 拓扑面积：
  3.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Biodegradable ocular implants and methods for treating ocular conditions
  申请人：Burkstrand J. Michael

  公开号：US20080089923A1

  公开（公告）日：2008-04-17

  Biodegradable ocular implants are described. The ocular implants include a bioactive agent that can be released within the eye to treat an ocular condition or indication. The implants can be used for the administration of a bioactive agent over prolonged periods of time. In some aspects the implants are formed of a matrix of natural biodegradable polysaccharides.

  可降解眼部植入物被描述。这些眼部植入物包括可以在眼内释放的生物活性剂，用于治疗眼部疾病或症状。这些植入物可用于在较长时间内给药生物活性剂。在某些方面，这些植入物由天然可降解多糖的基质形成。
• Coatings including natural biodegradable polysaccharides and uses thereof
  申请人：Chudzik J. Stephen

  公开号：US20070065481A1

  公开（公告）日：2007-03-22

  Biodegradable coatings and articles that include natural biodegradable polysaccharides are described. The coatings and articles are formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.

  描述了包括天然可生物降解多糖的可生物降解涂层和制品。这些涂层和制品由具有侧链偶联基团的多种天然可生物降解多糖形成。
• Latent stabilization of bioactive agents releasable from implantable medical articles
  申请人：Burkstrand Michael J.

  公开号：US20080154241A1

  公开（公告）日：2008-06-26

  Implantable medical articles comprising natural biodegradable polysaccharides are described. The polysaccharides can provide desirable release properties, and can also be degraded into products that can act as an excipient in the presence of the bioactive agent. In some aspects, the articles are ocular implants formed of a matrix of natural biodegradable polysaccharides. These ocular implants include a bioactive agent that can be released within the eye to treat an ocular condition or indication.

  描述了包含天然可生物降解多糖的可植入医疗器械。这些多糖可以提供理想的释放特性，并且在生物活性剂存在的情况下也可以降解为可作为赋形剂的产物。在某些方面，这些器械是由天然可生物降解多糖构成的眼部植入物。这些眼部植入物包括可以在眼内释放的生物活性剂，用于治疗眼部疾病或症状。
• Medicament incorporation matrix
  申请人：——

  公开号：US20020041899A1

  公开（公告）日：2002-04-11

  A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to be released from the matrix in a prolonged, controlled, predictable and effective manner in vivo. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer such as acrylamide.

  一种涂层组合物，包括其未交联和交联形式，用于从体内定位的医疗器械表面释放药物。一旦交联，涂层组合物提供适合在体内以延长、可控、可预测和有效的方式释放药物的凝胶基质。该组合物包括聚醚单体，如烷氧基聚（烷基乙二醇），含羧酸的单体，如（甲）丙烯酸，光衍生单体和亲水性单体，如丙烯酰胺。
• Coatings for medical articles including natural biodegradable polysaccharides
  申请人：Chudzik J. Stephen

  公开号：US20050255142A1

  公开（公告）日：2005-11-17

  Biodegradable coatings that include natural biodegradable polysaccharides are described. The coating is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.

  描述了包含天然可生物降解多糖的可生物降解涂层。该涂层由多种具有偶联基的天然可生物降解多糖形成。