3-(4-Methoxy-phenyl)-acrylic acid biphenyl-4-yl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(4-Methoxy-phenyl)-acrylic acid biphenyl-4-yl ester
• 英文别名: (4-phenylphenyl) (E)-3-(4-methoxyphenyl)prop-2-enoate
• 化学式: C₂₂H₁₈O₃
• 分子量: 330.4
• InChiKey: QURRVHVLRMVRFM-CXUHLZMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Methods and apparatus for ophthalmic devices including cycloidally oriented liquid crystal layers
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：EP2848984A2

  公开（公告）日：2015-03-18

  This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics.

  本发明公开了为眼科透镜提供可变光学插入物的方法和装置。液晶层可用于提供可变光学功能，在某些示例中，液晶层的对准层可按摆线方式进行图案化。在某些示例中，这种图案化可实现偏振相关透镜。能源能够为包括在眼科透镜内的可变光学插入件供电。在某些示例中，眼科透镜由硅酮水凝胶浇铸成型。各种眼科透镜实体可包括电活性液晶层，用于电控光学特性。
• Ophthalmic devices including cycloidally oriented liquid crystal layers
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：EP2851737A1

  公开（公告）日：2015-03-25

  This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer (570) may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples for left and right circular polarised light. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics.

  本发明公开了为眼科透镜提供可变光学插入物的方法和装置。液晶层（570）可用于提供可变光学功能，在某些示例中，液晶层的对准层可按摆线方式进行图案化。在某些示例中，该图案化可实现偏振相关透镜，用于左旋和右旋圆偏振光。能源能够为包括在眼科透镜内的可变光学插片供电。在某些示例中，眼科透镜由硅酮水凝胶浇铸成型。各种眼科透镜实体可包括电活性液晶层，用于电控光学特性。
• METHODS FOR FORMING VARIABLE OPTIC OPHTHALMIC DEVICES INCLUDING SHAPED LIQUID CRYSTAL ELEMENTS
  申请人：Johnson & Johnson Vision Care Inc.

  公开号：EP3264164A1

  公开（公告）日：2018-01-03

  This invention discloses methods and apparatus for providing an ophthalmic lens of variable optical power. The variable optic insert may have surfaces within that have differing radii of curvature. The variable optic insert may also comprise polarizing elements.An intermediate optic piece (1030) is formed to comprise a UV absorbing dye, allowing differential processing of regions on either side of the intermediate optic piece by UV irradiation (1115, 1120). In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics.

  本发明公开了提供可变光学功率的眼科透镜的方法和设备。可变光学插片内部可具有不同曲率半径的表面。中间光学片（1030）由紫外线吸收染料构成，允许通过紫外线照射（1115、1120）对中间光学片两侧的区域进行不同处理。在某些实施例中，眼科透镜由硅酮水凝胶浇铸成型。各种眼科透镜实体可包括电活性液晶层，用于电控折射特性。
• Methods for forming variable optic ophthalmic devices including shaped liquid crystal elements
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US10261344B2

  公开（公告）日：2019-04-16

  This invention discloses methods and apparatus for providing an ophthalmic lens of variable optical power. The variable optic insert may have surfaces within that have differing radii of curvature. The variable optic insert may also comprise polarizing elements. In some examples, an intermediate optic piece may be formed to comprise a UV absorbing dye, allowing differential processing of regions on either side of the intermediate optic piece. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics.

  本发明公开了提供可变光学功率的眼科透镜的方法和设备。可变光学镜片可具有不同曲率半径的表面。可变光学插入件还可包括偏振元件。在一些示例中，中间光学片可由紫外线吸收染料构成，从而允许对中间光学片两侧的区域进行不同处理。在某些实施例中，眼科透镜由硅酮水凝胶浇铸成型。各种眼科透镜实体可包括电活性液晶层，用于电控折射特性。
• Variable optic ophthalmic device including liquid crystal elements
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US10386653B2

  公开（公告）日：2019-08-20

  Methods and apparatuses for providing a variable optic insert into an ophthalmic lens as set forth. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics.

  在眼科透镜中安装可变光学镜片的方法和装置。 一种能源能够为包括在眼科透镜内的可变光学镜片供电。 在某些实施例中，眼科透镜由硅酮水凝胶浇铸成型。 各种眼科透镜实体可包括电活性液晶层，用于电控折射特性。