N,N-diethyl-4-[(Z)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]aniline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N,N-diethyl-4-[(Z)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]aniline
• 化学式: C18H23N2+
• 分子量: 267.4
• InChiKey: YCCVVPMYSGPISC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE
  申请人：Asahi Glass Company, Limited

  公开号：EP2889684A1

  公开（公告）日：2015-07-01

  Provided are: a prepolymer which is capable of forming a non-linear optical material that has excellent non-linear optical effect, heat resistance, withstand voltage and transparency; a curable material which contains the prepolymer; a coating composition which contains the curable material and a solvent; a non-linear optical material which is obtained by curing the curable material; an optical waveguide which uses the non-linear optical material; and a light control device which is provided with the optical waveguide. The present invention uses a prepolymer having a crosslinkable functional group, which is obtained by reacting one or more compounds (X) that are selected from the group consisting of compounds (X1), compounds (X2) and compounds (X3), a compound (Y) that is represented by formula (Y), a compound (Z) that has three or more phenolic hydroxyl groups, and an organic compound (B) that exerts a non-linear optical effect and has a reactive group.

  本发明提供了：一种能够形成非线性光学材料的预聚物，该材料具有优异的非线性光学效果、耐热性、耐电压性和透明度；一种包含该预聚物的可固化材料；一种包含该可固化材料和溶剂的涂层组合物；一种通过固化该可固化材料而获得的非线性光学材料；一种使用该非线性光学材料的光波导；以及一种配备该光波导的光控制装置。本发明使用了一种具有可交联官能团的预聚物，该预聚物是通过将一种或多种选自化合物（X1）、化合物（X2）和化合物（X3）组成的组的化合物（X）、由式（Y）表示的化合物（Y）、具有三个或多个酚羟基的化合物（Z）和具有非线性光学效应并具有活性基团的有机化合物（B）反应而得到的。
• Methods for dye selection for protein melt temperature determinations
  申请人：LIFE TECHNOLOGIES CORPORATION

  公开号：US10024863B2

  公开（公告）日：2018-07-17

  According to the present teachings, compositions, kits, and methods for protein melt analysis are provided that utilizing one or more fluorophore dyes. In some embodiments, a method comprises preparing a sample by mixing at least one protein with two or more dyes, and applying a controlled heating, while recording the fluorescence emission of the sample. The methods can be used, for example, for screening conditions for optimized protein stability, screening for ligands that bind and enhance protein stability (e.g., protein-protein interactions), screening for mutations for enhanced stability, screening crystallization conditions for protein stability, screening storage conditions for protein stability, and screening conditions in which a protein will be used (e.g., production conditions, treatment conditions, etc.) for protein stability.

  根据本教导，提供了利用一种或多种荧光团染料进行蛋白质熔体分析的组合物、试剂盒和方法。在某些实施方案中，方法包括通过将至少一种蛋白质与两种或两种以上染料混合来制备样品，并进行受控加热，同时记录样品的荧光发射。这些方法可用于筛选优化蛋白质稳定性的条件、筛选结合并提高蛋白质稳定性的配体（如蛋白质-蛋白质相互作用）、筛选提高稳定性的突变、筛选提高蛋白质稳定性的结晶条件、筛选提高蛋白质稳定性的储存条件，以及筛选提高蛋白质稳定性的蛋白质使用条件（如生产条件、处理条件等）。
• Compositions and methods for intracellular delivery
  申请人：——

  公开号：US20040242416A1

  公开（公告）日：2004-12-02

  The invention relates to intracellular deliver alcoholic lipid compositions for medical, cosmetic, research, diagnostic, veterinary, agriculture or pharmaceutical use containing phospholipid(s), ethanol (or other C2-C4 such volatile alcohols), water, at least one active molecule, optional addition of glycols or/and other additions for delivery to cells of an entrapped, attached, adsorbed, completed molecule(s).

  本发明涉及用于医疗、美容、研究、诊断、兽医、农业或制药的细胞内递送酒精脂质组合物，该组合物含有磷脂、乙醇（或其他 C2-C4 类挥发性醇）、水、至少一种活性分子、可选择添加的乙二醇或/和其他添加物，用于向细胞递送夹带、附着、吸附的完整分子。
• COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY
  申请人：YISSUM RESEARCH DEVELOPMENT COMPANYOF THE HEBREW UNIVERSITY OF JERUSALEM

  公开号：EP1411897A2

  公开（公告）日：2004-04-28
• Compositions and Methods for Intracellular Delivery
  申请人：Touitou Elka

  公开号：US20100298420A1

  公开（公告）日：2010-11-25

  The invention relates to intracellular delivery of alcoholic lipid compositions for medical, cosmetic, research, diagnostic, veterinary, agriculture or pharmaceutical use containing phospholipid(s), ethanol (or other C2-C4 such volatile alcohols), water, at least one active molecule, optional addition of glycols and/or other additions for delivery to cells of an entrapped, attached, adsorbed, and/or complexed molecule(s).