Benzoic acid, trichloromethoxy- | 73506-98-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzoic acid, trichloromethoxy-
• 英文别名: 2-(trichloromethoxy)benzoic acid
• CAS: 73506-98-6
• 化学式: C₈H₅Cl₃O₃
• 分子量: 255.5
• InChiKey: VJDXVKGZXXXKQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PROCESS FOR PRODUCING AMINOALKYLSULFONIC ACID AND METHOD OF SALT EXCHANGE FOR SALT THEREOF
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1548002A1

  公开（公告）日：2005-06-29

  The present invention relates to a method for efficiently producing an aminoalkylsulfonic acid in an industrial scale, and provides    "a process for producing an aminoalkylsulfonic acid represented by the general formula [2]:    wherein R1 and R2 are each independently a hydrogen atom, an alkyl group, an aryl group or an aralkyl group; and R3 and R4 are each independently a hydrogen atom or an alkyl group, comprising reacting an aminoalkylsulfonate salt represented by the general formula [1]:    wherein M is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 to R4 are the same as described above,    an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon atoms, carboxylic acids having 2 to 12 carbon atoms and dimethylformamide, with an organic acid; and    a method of salt exchange for an aminoalkylsulfonate salt represented by the general formula [1']:    wherein M' is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 and R4 are the same as described above, comprising reacting an aminoalkylsulfonate salt represented by the above general formula [2] with a hydroxide represented by the general formula [6]:         M'OH     [6]    wherein M' is the same as described above, in an alcohol or water".

  本发明涉及一种在工业规模上高效生产氨基磺酸的方法，并提供“一种生产由通式[2]表示的氨基磺酸的方法：其中R1和R2分别是氢原子、烷基、芳基或芳基烷基；R3和R4分别是氢原子或烷基的氨基磺酸盐发生反应所得的方法，通式[1]表示如下：其中M是碱金属原子、有机铵离子或铵离子；R1至R4与上述相同，其水溶液或将任何一种溶解于水溶性有机溶剂中的溶液，所选的有1至3个碳原子的醇、有2至12个碳原子的羧酸和二甲基甲酰胺，与有机酸反应；以及氨基磺酸盐交换的方法，通式[1']表示如下：其中M'是碱金属原子、有机铵离子或铵离子；R1和R4与上述相同，包括将上述通式[2]表示的氨基磺酸盐与通式[6]表示的氢氧化物发生反应：M'OH [6]其中M'与上述相同，在醇或水中”。
• Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof
  申请人：Kimura Takuhiro

  公开号：US20050261370A1

  公开（公告）日：2005-11-24

  A process for producing an aminoalkylsulfonic acid of formula [2]: wherein R 1 and R 2 are each independently hydrogen, alkyl, aryl or aralkyl; and R 3 and R 4 are each independently hydrogen or alkyl, comprising reacting an aminoalkylsulfonate salt of formula [1]: wherein M is alkali metal, organic ammonium or ammonium ion; and R 1 to R 4 are as described above, an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon, carboxylic acids having 2 to 12 carbon and dimethylformamide, with an organic acid; and a method of salt exchange for an aminoalkylsulfonate salt of formula [1′]: wherein M′ is alkali metal, organic ammonium or ammonium ion; and R 1 and R 4 are as described above, comprising reacting the aminoalkylsulfonate salt formula [2] with a hydroxide of formula [6]: M′OH  [6] wherein M′ is as described above, in alcohol or water.

  一种生产化学式[2]的氨基烷基磺酸的方法：其中R1和R2各自独立地表示氢、烷基、芳香基或芳基烷基；R3和R4各自独立地表示氢或烷基，包括反应化学式[1]的氨基烷基磺酸盐：其中M为碱金属、有机铵或铵离子；R1至R4如上所述，其水溶性有机溶剂中的水溶性溶液或溶解其中任何一种的溶液，所选的有机酸；以及化学式[1']的氨基烷基磺酸盐的盐交换方法：其中M'为碱金属、有机铵或铵离子；R1和R4如上所述，包括将氨基烷基磺酸盐化学式[2]与化学式[6]的氢氧化物反应：M'OH [6]，其中M'如上所述，在醇或水中。
• Hybrid onium salt
  申请人：Ishihara Masami

  公开号：US20050020710A1

  公开（公告）日：2005-01-27

  The present invention relates to a hybrid type onium salt having an iodonium salt and a sulfonium salt in the molecule, useful, for example, as a cationic type photopolymerization initiator and an acid generator for a chemically amplified resist and provides a hybrid type onium salt shown by the general formula [1]: [wherein R 1 to R 3 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 1 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 1 is an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; and R 4 is an alkyl group, an alkenyl group, an aryl group or an aralkyl group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted or a group shown by the general formula [2]: (wherein R 5 to R 7 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 2 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 2 an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; A 3 is a counter anion; m is an integer of 0 to 4; and two ns are each independently an integer of 0 to 5); A 1 and A 2 are each independently a counter anion; and m and n are the same as described above], and a polymerization initiator or an acid generator, comprising said onium salt.

  本发明涉及一种杂化型离子盐，其分子中具有碘化离子盐和亚砜盐，例如，作为阳离子型光聚合引发剂和化学放大型抗蚀剂的酸发生剂有用，并提供由通式[1]所示的杂化型离子盐：[其中R1至R3分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q1是直链、氧原子、硫原子或较低的烷基链；T1是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；R4是烷基、烯丙基、芳基或芳基烷基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基或由通式[2]所示的基：（其中R5至R7分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q2是直链、氧原子、硫原子或较低的烷基链；T2是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；A3是一个对离子；m是0到4的整数；两个n各自独立地是0到5的整数）；A1和A2各自独立地是一个对离子；m和n与上述描述相同]，以及包含该离子盐的聚合引发剂或酸发生剂。
• Sulfonium salt compounds
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1113005A1

  公开（公告）日：2001-07-04

  A triphenyl sulfonium salt compound shown by the general formula [1] or [3]. (wherein R1 and R2 are each independently a hydrogen atom or a lower alkyl group, provided that at least one of R1 and R2 are a lower alkyl group, R3s are each independently an alkyl group, n is an integer of 0 to 3, i is an integer of 1 to 3, j is an integer of 0 to 2, provided that i+j=3, Y- is an anion derived from a sulfonic acid shown by the general formula [2]         R4―SO3H     [2] [wherein R4 is an alkyl group or an aryl group which may have as a substituent an alkyl group]). (wherein X is a phenyl group which has a substituent at an ortho- and/or a meta-position, m is an integer of 1 to 3, q is an integer of 0 to 2, provided that m+q=3, p is 1 or 2 and Zp- is an anion derived from a carboxylic acid).

  通式[1]或[3]所示的三苯基锍盐化合物。 (其中，R1 和 R2 各自独立地为氢原子或低级烷基，条件是 R1 和 R2 中至少有一个是低级烷基；R3s 各自独立地为烷基；n 为 0 至 3 的整数；i 为 1 至 3 的整数；j 为 0 至 2 的整数，条件是 i+j=3 ；Y- 是由通式[2]所示磺酸衍生的阴离子。 R4-SO3H [2] [其中 R4 为烷基或芳基，其取代基可为烷基]）。 (其中 X 是在正位和/或偏位上具有取代基的苯基，m 是 1 至 3 的整数，q 是 0 至 2 的整数，条件是 m+q=3，p 是 1 或 2，Zp- 是衍生自羧酸的阴离子）。
• CLEANING AGENT FOR THERMOSTATIC CHAMBERS
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1865049A1

  公开（公告）日：2007-12-12

  [PROBLEMS] The present invention provides a novel cleaner having bacteria-proof, fungi-proof and algae-proof effects, which is added to a reaction thermostat using water as medium in scientific apparatus, particularly a thermostatic water bath in an automatic analyzer. [SOUTLIN] A cleaner for a thermostatic water bath, which comprises a quaternary ammonium salt as shown by the general formula [1] described below and/or a preservative agent having amphoteric surface activity, and a surface active agent, wherein R1 to R4 independently represent an alkyl group, provided that at least one among R1 to R4 is an alkyl group having 8 to 18 carbon atoms, and at least one among them is a lower alkyl group having 1 to 3 carbon atoms; and X- represents an anion derived from a carboxylic acid having two or more carbon atoms; and a cleaning method of a thermostatic water bath, wherein the cleaner is added to a thermostatic water bath.

  问题 本发明提供了一种具有防菌、防霉、防藻效果的新型清洁剂，该清洁剂被添加到以水为介质的反应恒温器中，用于科学仪器，特别是自动分析仪中的恒温水浴。 [苏特琳］ 一种用于恒温水浴的清洁剂，它由下述通式[1]所示的季铵盐和/或具有两性表面活性的防腐剂以及表面活性剂组成、 其中 R1 至 R4 独立地代表烷基，条件是 R1 至 R4 中至少有一个是具有 8 至 18 个碳原子的烷基，且其中至少有一个是具有 1 至 3 个碳原子的低级烷基；X- 代表从具有两个或两个以上碳原子的羧酸衍生的阴离子；以及一种恒温水浴的清洁方法，其中该清洁剂被添加到恒温水浴中。