hydron;3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-1-ol;dichloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hydron;3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-1-ol;dichloride
• 化学式: C22H32Cl2N2O2
• 分子量: 427.4
• InChiKey: KVKUGOLSESPAPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.96
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  35.9
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Compositions and methods for the treatment of pain
  申请人：GM Pharmaceuticals, Inc.

  公开号：US10987365B2

  公开（公告）日：2021-04-27

  The claimed invention relates to compositions that may be in a form of a liquid, solid, gel, cream or gel capsule comprising an analgesic, and methods for administering these compositions for treatment of patients suffering from various forms of pain.

  本发明涉及可为液体、固体、凝胶、乳膏或凝胶胶囊形式的包含镇痛剂的组合物，以及使用这些组合物治疗各种形式疼痛患者的方法。
• PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF
  申请人：Pediamed Pharmaceuticals, Inc.

  公开号：EP1641446A1

  公开（公告）日：2006-04-05
• INLINE APPLICATION OF COATINGS
  申请人：Cook Medical Technologies LLC

  公开号：EP1993741B1

  公开（公告）日：2014-03-19
• ZEIN COATED MEDICAL DEVICE
  申请人：Med Institute, Inc.

  公开号：EP1981560B1

  公开（公告）日：2010-09-08
• Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof
  申请人：PediaMed Pharmaceuticals, Inc.

  公开号：US20040259809A1

  公开（公告）日：2004-12-23

  The present invention provides pharmaceutical compositions including a sedating antihistamine and a stimulant, and methods of use thereof. The stimulant reduces the sedation caused by the antihistamine, thereby allowing potent, but sedating, antihistamines to be used effectively.