1,3-Diazetidin-2-one, 1,3-bis(4-((4-isocyanatophenyl)methyl)phenyl)-4-((4-((4-isocyanatophenyl)methyl)phenyl)imino)- | 31107-36-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-Diazetidin-2-one, 1,3-bis(4-((4-isocyanatophenyl)methyl)phenyl)-4-((4-((4-isocyanatophenyl)methyl)phenyl)imino)-
• 英文别名: 1,3-bis[4-[(4-isocyanatophenyl)methyl]phenyl]-4-[4-[(4-isocyanatophenyl)methyl]phenyl]imino-1,3-diazetidin-2-one
• CAS: 31107-36-5
• 化学式: C₄₄H₃₀N₆O₄
• 分子量: 706.7
• InChiKey: NFAVIZJKOVSCKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.7
• 重原子数：
  54
• 可旋转键数：
  12
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  124
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  4,4'-二苯甲烷二异氰酸酯、2,4'-二苯甲烷二异氰酸酯和2,2'-二苯甲烷二异氰酸酯的混合物 、 N,N’-甲四基二[4-[(4-异氰酸根合苯基)甲基]-苯胺 生成 1,3-Diazetidin-2-one, 1,3-bis(4-((4-isocyanatophenyl)methyl)phenyl)-4-((4-((4-isocyanatophenyl)methyl)phenyl)imino)-
  参考文献：
  名称：

  IVANOV, M. G.;GOLOV, V. G.;ROGULEV, V. A.;MUSHKIN, YU. I.;VODOPYANOV, V. +, XIM. PROM-ST,(1988) N 4, 208-210

  摘要：

  DOI：

文献信息

• Methods of treating and/or preventing nail disorders and/or improving the appearance of a nail
  申请人：CHESSON LABORATORY ASSOCIATES, INC.

  公开号：US10987376B2

  公开（公告）日：2021-04-27

  Systems and/or methods of treating and/or preventing nail disorders are disclosed herein. Also, disclosed herein are systems and/or methods of improving the appearance of a nail. A preferred embodiment of the present invention comprises a method of treating and/or preventing a nail disorder in a subject comprising topically applying a composition comprising a poly(urea-urethane)polymer and/or a poly(urea-urethane) pre-polymer to a nail of said subject, thereby treating and/or preventing said nail disorder.

  本文公开了治疗和/或预防指甲疾病的系统和/或方法。此外，本文还公开了改善指甲外观的系统和/或方法。本发明的一个优选实施方案包括一种治疗和/或预防受试者指甲疾病的方法，该方法包括将一种包含聚脲-聚氨酯聚合物和/或聚脲-聚氨酯预聚物的组合物局部施用到所述受试者的指甲上，从而治疗和/或预防所述指甲疾病。
• IVANOV, M. G.;GOLOV, V. G.;ROGULEV, V. A.;MUSHKIN, YU. I.;VODOPYANOV, V. +, XIM. PROM-ST,(1988) N 4, 208-210
  作者：IVANOV, M. G.、GOLOV, V. G.、ROGULEV, V. A.、MUSHKIN, YU. I.、VODOPYANOV, V. +

  DOI：——

  日期：——
• METHOD OF PRODUCING A URETONIMINE-MODIFIED ISOCYANATE COMPOSITION
  申请人：BASF SE

  公开号：EP2046858A1

  公开（公告）日：2009-04-15
• POLY(UREA-URETHANE) COMPOSITIONS USEFUL AS TOPICAL MEDICAMENTS AND METHODS OF USING THE SAME
  申请人：Chesson Laboratory Associates, Inc.

  公开号：EP2207535B1

  公开（公告）日：2014-08-27
• URETONIMINE-MODIFIED ISOCYANATE COMPOSITION AND METHOD OF FORMING THE SAME
  申请人：SAVINO THOMAS

  公开号：US20070213432A1

  公开（公告）日：2007-09-13

  A uretonimine-modified isocyanate composition having reduced color and a method of forming the same is disclosed. The method of forming the uretonimine-modified isocyanate composition comprises providing a polyisocyanate composition having two or more isocyanate groups and reacting the polyisocyanate composition at a temperature in a range of from about 80° C. to about 130° C. and in the presence of a catalyst. The reaction of the polyisocyanate composition is quenched with a quenching agent and a color inhibitor having a low basicity and having at least one hindered amine group is added. The uretonimine-modified isocyanate composition has a color value corresponding to an a* value of greater than about −10 and a b* value less than about 10 as defined by CIE L*a*b* (CIELAB) Color Space Specification and undergoes a % NCO group decrease of less than about 6 %.