1,1-bis(cyanoethyl)hydrazine | 5678-77-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,1-bis(cyanoethyl)hydrazine
• 英文别名: 3,3'-hydrazono-di-propionitrile；N,N-Bis-(2-cyan-aethyl)-hydrazin；3,3'-Hydrazono-di-propionitril；N,N-Bis-(β-cyanaethyl)-hydrazin；N,N-Di-(β-cyanethyl)-hydrazin；1,1-Bis-(2-cyan-ethyl)-hydrazin；3,3'-(Hydrazine-1,1-diyl)dipropanenitrile；3-[amino(2-cyanoethyl)amino]propanenitrile
• CAS: 5678-77-3
• 化学式: C₆H₁₀N₄
• 分子量: 138.172
• InChiKey: QYOZRCXKUZAYDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  76.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,1-bis(cyanoethyl)hydrazine 以 苯 为溶剂， 生成 1.1-Bis-<2-cyan-aethyl>-4-phenyl-2-phenylcarbamyl-semicarbazid
  参考文献：
  名称：

  Iorio,M.A., Gazzetta Chimica Italiana, 1964, vol. 94, p. 1391 - 1418

  摘要：

  DOI：
• 作为产物：
  描述：

  丙烯腈 在 一水合肼 作用下， 生成 1,1-bis(cyanoethyl)hydrazine
  参考文献：
  名称：

  Iorio,M.A., Gazzetta Chimica Italiana, 1964, vol. 94, p. 1391 - 1418

  摘要：

  DOI：

文献信息

• Potential anticonvulsants. IX. Some isatin hydrazones and related compounds
  作者：Frank D. Popp

  DOI：10.1002/jhet.5570210614

  日期：1984.11

  A number of hydrazines, hydrazides, and related compounds have been condensed with isatin and substituted isatins. The anticonvulsant activity of these compounds is reported.

  许多肼，酰肼和相关化合物已与Isatin和取代的Isatin缩合。报道了这些化合物的抗惊厥活性。
• Reaction of 1,1-disubstituted hydrazines with bromine in the presence of aryl- and heteroarylnitroso compounds in acid media: A general method for the synthesis of 1-aryl(heteroaryl)-3,3-disubstituted triazene 1-oxides
  作者：S. G. Zlotin、O. V. Prokshits、N. F. Karpenko、Yu. A. Strelenko、O. A. Luk'yanov

  DOI：10.1007/bf00864338

  日期：1992.8

  We have worked out a method for the synthesis of 1,3,3-trisubstituted triazene 1-oxides based upon reaction of 1,1-disubstituted hydrazines with bromine in the presence of aryl- and heteroarylnitroso compounds in acid media. Obtained are a broad range of triazene 1-oxides, among which hitherto unknown compounds of the series of pyrazole and 3,3-dialkyltriazene 1-oxides that contain functional groups at the alkyl part of the molecule. We propose a reaction scheme which includes in situ formation of diazenium cations and reaction of them with nitroso compounds that are present in the system. By means of PMR, C-13, and N-14 NMR spectroscopy, and mass spectroscopy, it has been shown that in all the prepared compounds the oxidated nitrogen atom is at the N1 position of the triazene N-oxide group.
• Notes- Synthesis and Some Reactions of 1,1-Bis(2-cyanoethyl)hydrazine.
  作者：John Lynn

  DOI：10.1021/jo01065a617

  日期：1961.6
• Mugno; Bornengo, Gazzetta Chimica Italiana, 1956, vol. 86, p. 451,458
  作者：Mugno、Bornengo

  DOI：——

  日期：——
• POPP, F. D., J. HETEROCYCL. CHEM., 1984, 21, N 6, 1641-1645
  作者：POPP, F. D.

  DOI：——

  日期：——