hydroxypropyl-o-benzenedicarboxylic acid | 1005516-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hydroxypropyl-o-benzenedicarboxylic acid
• 英文别名: hydroxypropylbenzenedicarboxylic acid；3-(3-Hydroxypropyl)phthalic acid
• CAS: 1005516-60-8
• 化学式: C₁₁H₁₂O₅
• 分子量: 224.213
• InChiKey: XPJGPHUQVCCDJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  94.8
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  Diethyl 3-(3-hydroxypropyl)benzene-1,2-dicarboxylate 在 水 、 sodium hydroxide 、 盐酸 作用下， 以 1,4-二氧六环 、 水 为溶剂， 以58%的产率得到hydroxypropyl-o-benzenedicarboxylic acid
  参考文献：
  名称：

  邻苯二甲酸衍生物的金属β-内酰胺酶抑制活性

  摘要：

  4-丁基-3-甲基邻苯二甲酸被认为是金属β-内酰胺酶抑制剂。取代邻苯二甲酸的结构-活性关系研究提供了3-苯基邻苯二甲酸衍生物作为有效的IMP-1抑制剂。另一方面，用4-羟基苯基邻苯二甲酸衍生物进行的3-取代显示出与比安培南（BIPM）对产生IMP-1的铜绿假单胞菌的有效组合作用。

  DOI：

  10.1016/j.bmcl.2009.07.018

文献信息

• UNSATURATED POLYESTER RESINS
  申请人：Ashland Inc.

  公开号：EP1131372B1

  公开（公告）日：2006-06-14
• US6268464B1
  申请人：——

  公开号：US6268464B1

  公开（公告）日：2001-07-31
• [EN] UNSATURATED POLYESTER RESINS<br/>[FR] RESINES DE POLYESTER INSATURE
  申请人：NESTE CHEMICALS OY

  公开号：WO2000023495A1

  公开（公告）日：2000-04-27

  The invention relates to unsaturated polyester resins with higher molecular weight, low viscosity and high solubility specially in reactive diluents. The invention also relates to a method for manufacture of such unsaturated polyester resins and to use thereof in various applications such as gelcoats. The unsaturated polyester resin comprises 20-85 wt.% of at least one unsaturated polyester having a molecular weight of 2000-6000, prepared from 1) 30-70 mol%, preferably 40-60 mol% of at least two unsaturated carboxylic acids or derivatives thereof and at least one of them is an unsaturated aromatic carboxylic acid or a derivative thereof and optionally of one or more carboxylic acids and derivatives thereof, 2) 30-70 mol%, preferably 40-60 mol% of at least two diols and at least one of them is an aliphatic branched diol, preferably 2,2,4-trimethyl-1,3-pentanediol and/or 2-butyl-2-ethyl-1,3-propanediol and the amount of the aliphatic branched diol/diols is 0.5-8 mol%, preferably 2-6 mol%, 3) 0.5-10 mol%, preferably 2-6 mol% of at least one monoalcohol, 4) optionally a modifying chemical/chemicals and the total amount of monoalcohols and modifying chemicals is 0.5-20 mol%, preferably 1-15 mol%, 5) optionally 0.5-20 mol%, preferably 1-10 mol% of a polyhydric alcohol/alcohols having at least three hydroxyl groups, and 15-50 wt.% of at least one reactive diluent.
• [EN] UNSATURATED POLYESTER GEL COATS WITH ANTIFOULING PROPERTIES<br/>[FR] REVETEMENT GELIFIE DE POLYESTER INSATURE POSSEDANT DES PROPRIETES ANTISALISSURES
  申请人：ASHLAND INC

  公开号：WO2001074953A1

  公开（公告）日：2001-10-11

  This invention relates to unsaturated polyester gel coats with antifouling properties and to the use of unsaturated polyester gel coats containing antifouling agents for applications, such as marine coatings. Unsaturated polyester gel coats with antifouling properties comprise antifouling agents selected from the group consisting of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, cyclopropyl-N'-(1,1-dimethylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine and N-[(fluoro-dichloro-methyl)thio]-phthalimide or a mixtures thereof. Additionally the invention relates to the preparation of unsaturated polyester gel coats having antifouling properties.