2-Methylthio-2,3-dimethylbutane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-Methylthio-2,3-dimethylbutane
• 英文别名: 2,3-dimethyl-2-methylsulfanylbutane
• 化学式: C₇H₁₆S
• 分子量: 132.27
• InChiKey: BKWHGDIDEVJYBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] BETA-LACTAMASE INHIBITORS<br/>[FR] INHIBITEURS DE BÊTA-LACTAMASES
  申请人：VENATORX PHARMACEUTICALS INC

  公开号：WO2017100537A1

  公开（公告）日：2017-06-15

  Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

  本文描述了调节β-内酰胺酶活性的化合物和组合物。在某些实施例中，所述化合物抑制β-内酰胺酶。在特定实施例中，所述化合物在治疗细菌感染方面是有用的。
• Sulfur compounds as inhibitors of Hepatitis C virus NS3 serine protease
  申请人：Bennett Frank

  公开号：US20070042968A1

  公开（公告）日：2007-02-22

  The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

  本发明揭示了具有HCV蛋白酶抑制活性的新化合物，以及制备这些化合物的方法。在另一种实施方式中，本发明揭示了包含这些化合物的药物组合物，以及使用它们治疗与HCV蛋白酶相关的疾病的方法。
• Inhibitors of Hepatitis C NS3 Protease
  申请人：Bailey Murray D.

  公开号：US20100087382A1

  公开（公告）日：2010-04-08

  Compounds of formula I: wherein R 1 , R 2 , R 2a , R 3 , R 4 and R 5 are defined herein, are useful as inhibitors of the HCV NS3 protease.

  式I的化合物： 其中R1、R2、R2a、R3、R4和R5在此定义，可用作HCV NS3蛋白酶的抑制剂。
• NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS
  申请人：Saksena Anil K.

  公开号：US20110117057A1

  公开（公告）日：2011-05-19

  The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

  本发明披露了具有HCV蛋白酶抑制活性的新化合物，以及制备这些化合物的方法。在另一种实施方式中，本发明披露了包含这些化合物的制药组合物，以及使用它们治疗与HCV蛋白酶相关的疾病的方法。
• POLYGERMANE COMPOUND WITH SULPHUR-CONTAINING ORGANIC GROUP DISPLAYING HIGH HEAT RESISTANCE
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2537852A1

  公开（公告）日：2012-12-26

  There is provided a polygermane compound forming a film having a high refractive index and thermal stability, and containing a sulfur atom-containing organic group as a group bonded to a germanium atom. A polygermane compound comprising a sulfur atom-containing organic group as a group bonded to a germanium atom, in which the sulfur atom-containing organic group is a group of Formula [1]:         -L-Z     [1] where L is a single bond, a C1-6 alkylene group, or a C4-20 arylene group optionally substituted with a C1-6 alkyl group; and Z is a C1-20 sulfide group, a C1-14 cyclic sulfide group optionally substituted with a C1-6 alkyl group, a C2-20 alkyl group containing a sulfide bond, or a C5-20 aralkyl group containing a sulfide bond, with a proviso that when L is a single bond, Z is not a C1-20 sulfide group.

  本发明提供了一种聚锗烷化合物，其形成的薄膜具有高折射率和热稳定性，并含有一个含硫原子的有机基团作为与锗原子键合的基团。一种聚锗烷化合物，包含一个作为与锗原子键合的基团的含硫原子有机基团，其中含硫原子有机基团为式[1]的基团： -L-Z [1] 其中 L 是单键、C1-6 亚烷基或任选被 C1-6 烷基取代的 C4-20 芳烷基；Z 是 C1-20 硫化物基团、任选被 C1-6 烷基取代的 C1-14 环硫化物基团、含有硫化物键的 C2-20 烷基或含有硫化物键的 C5-20 芳烷基，但当 L 是单键时，Z 不是 C1-20 硫化物基团。