5-(p-Aminophenyl)-1,2,3,4-tetrahydroxypentane | 144069-91-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-(p-Aminophenyl)-1,2,3,4-tetrahydroxypentane
• 英文别名: 5-(4-aminophenyl)pentane-1,2,3,4-tetrol
• CAS: 144069-91-0
• 化学式: C₁₁H₁₇NO₄
• 分子量: 227.26
• InChiKey: MRNNKNGLQUJDHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  107
• 氢给体数：
  5
• 氢受体数：
  5

文献信息

• [EN] POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF<br/>[FR] PROCEDE DE SELECTION POSITIVE, COMPOSES, CELLULES HOTES ET LEUR UTILISATION
  申请人：CUBIST PHARM INC

  公开号：WO2001077366A1

  公开（公告）日：2001-10-18

  This invention relates to a positive selection method, compounds useful for the positive selection and appropriate hosts. The method permits one to select a host, or auxotroph, which may be a prokaryote or an eukaryote, based on the ability of the host to express an enzyme(s) capable of catalyzing a reaction that converts a precursor molecule into a molecule or factor necessary for the host's survival. This invention encompasses methods useful to find new enzymes expressing a desired activity, methods of selecting host cells, methods of maintaining a plasmid within a host that do not utilize antibiotics, and methods of expressing proteins or other materials for commercial production purposes.