2-{[6-(Decanoylamino)hexanoyl]oxy}benzene-1-sulfonic acid | 173740-87-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 2-{[6-(Decanoylamino)hexanoyl]oxy}benzene-1-sulfonic acid
• 英文别名: 2-[6-(decanoylamino)hexanoyloxy]benzenesulfonic acid
• CAS: 173740-87-9
• 化学式: C₂₂H₃₅NO₆S
• 分子量: 441.6
• InChiKey: GOKVKLCCWGRQJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  30
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  118
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• [EN] CYCLOHEXENE DERIVATIVES AS FRAGRANCES AND/OR FLAVORS<br/>[FR] DÉRIVÉS DE CYCLOHEXÈNE COMME FRAGRANCES ET/OU ARÔMES
  申请人：SYMRISE AG

  公开号：WO2017133754A1

  公开（公告）日：2017-08-10

  The present invention relates to novel cyclohexene derivatives selected from the group consisting of formula (la) and/or (lb), and the use of the cyclohexene derivatives and their isomers as fragrances, especially as fragrances with a rhubarb odour tonality, and fragrance and/or flavouring compositions as well as consumer products, comprising the cyclohexene derivatives of formula (la) and/or (lb).

  本发明涉及从化学式（Ia）和/或（Ib）所述的新型环己烯衍生物中选择的环己烯衍生物，以及将环己烯衍生物及其异构体用作香料，特别是具有大黄气味音调的香料，以及包含化学式（Ia）和/或（Ib）所述的环己烯衍生物的香料和/或调味剂组合物以及消费产品。
• MID-CHAIN BRANCHED PERACIDS AND PERACID PRECURSORS
  申请人：——

  公开号：US20020161258A1

  公开（公告）日：2002-10-31

  Mid-chain branched peracids and peracid precursors useful in laundry and cleaning compositions, especially granular and liquid detergent compositions are disclosed. These peracids and precursors are suitable for formulation with a wide range of detergent adjuncts for the purpose of providing improved cleaning systems, especially for use in detergent compositions which will be used in laundry processes involving low water temperature wash conditions. The present invention also relates to novel mid-chain branched peracids and precursors for use in the compositions of the present invention.

  本发明涉及中链支化过酸和过酸前体，用于洗涤和清洁组合物，特别是颗粒和液体洗涤剂组合物。这些过酸和前体适用于与各种洗涤剂助剂配方，以提供改进的清洁系统，特别是用于洗涤剂组合物中，该组合物将用于涉及低水温洗涤条件的洗涤过程。本发明还涉及用于本发明组合物的新型中链支化过酸和前体。
• Laundry detergent compositions comprising zwitterionic polyamines and mid-chain branched surfactants
  申请人：The Procter & Gamble Company

  公开号：US20040072718A1

  公开（公告）日：2004-04-15

  The present invention relates to laundry detergent compositions which provide enhance hydrophilic soil cleaning benefits, said compositions comprising: a) from about 0.01% by weight of a zwitterionic polyamine; b) from about 0.01% by weight, of a surfactant system comprising: i) from 0% to 80% by weight, of a mid-chain branched alkyl sulfate surfactant; ii) from 0% to 80% by weight, of a mid-chain branched aryl sulfonate surfactant; iii) optionally from 0.01% by weight, of a surfactant selected from the group consisting of anionic, nonionic, cationic, zwitterionic, ampholytic surfactants, and mixtures thereof; c) the balance carriers and other adjunct ingredients.

  本发明涉及洗衣清洁剂组合物，其提供增强亲水性土壤清洁效益，所述组合物包括：a）约0.01％重量的双性聚胺；b）约0.01％重量的表面活性剂系统，包括：i）0％至80％重量的中链支化烷基硫酸盐表面活性剂；ii）0％至80％重量的中链支化芳基磺酸盐表面活性剂；iii）可选地，0.01％重量的表面活性剂，所选表面活性剂来自阴离子、非离子、阳离子、双性离子、两性表面活性剂和其混合物；c）平衡载体和其他辅助成分。
• Laundry detergent compositions comprising polyamines and mid-chain branched surfactants
  申请人：——

  公开号：US20040077514A1

  公开（公告）日：2004-04-22

  The present invention relates to laundry detergent compositions which provide enhance hydrophilic soil cleaning benefits, said compositions comprising: a) from about 0.01% by weight of a polyamine, said polyamine selected from the group consisting of: i) polyamines comprising two or more backbone nitrogens; ii) polyamines comprising one or more cationic backbone nitrogens; iii) polyamines comprising one or more alkoxylated backbone nitrogens; iv) polyamines comprising one or more cationic backbone nitrogens and one or more alkoxylated backbone nitrogens; and v) mixtures thereof; b) from about 0.01% by weight, of a surfactant system comprising: i) from 0% to 80% by weight, of a mid-chain branched alkyl sulfate surfactant; ii) from 0% to 80% by weight, of a mid-chain branched aryl sulfonate surfactant; iii) optionally from 0.01% by weight, of a surfactant selected from the group consisting of anionic, nonionic, cationic, zwitterionic, ampholytic surfactants, and mixtures thereof; c) the balance carriers and other adjunct ingredients.

  本发明涉及洗衣剂组合物，其提供增强亲水性土壤清洁效益，所述组合物包括：a）约0.01％重量的多胺，所述多胺选自以下组合中的一种或多种：i）包含两个或更多骨架氮的多胺；ii）包含一个或多个阳离子骨架氮的多胺；iii）包含一个或多个烷氧基化骨架氮的多胺；iv）包含一个或多个阳离子骨架氮和一个或多个烷氧基化骨架氮的多胺；和v）其混合物；b）约0.01％重量的表面活性剂系统，包括：i）从0％到80％重量的中链支化烷基硫酸盐表面活性剂；ii）从0％到80％重量的中链支化芳烃磺酸盐表面活性剂；iii）可选地从阴离子、非离子、阳离子、双性离子、两性表面活性剂和其混合物中选择的约0.01％重量的表面活性剂；c）余量的载体和其他辅助成分。
• Substituted azabicyclic compounds
  申请人：——

  公开号：US20020173527A1

  公开（公告）日：2002-11-21

  This invention is directed to physiologically active compounds of formula (I) 1 wherein 2 represents a bicyclic ring, system, of 9 ring members, in which the ring 3 is an oxazole, and the ring 4 is a benzene ring; R 1 represents hydrogen or a straight- or branched-chain alkyl group of 1 to about 4 carbon atoms, optionally substituted by hydroxy or one or more halogen atoms, or when Z 1 represents a direct bond R 1 may also represent a lower alkenyl or lower alkynyl group, or a formyl group; R 2 represents hydrogen, alkenyl, alkoxy, alkyl, alkylsulphinyl, alkylsulphonyl, alkylthio, aryl, arylalkyloxy, arylalkylsulphinyl, arylalkylsulphonyl, arylalkylthio, aryloxy, arylsulphinyl, arylsulphonyl, arylthio, cyano, cycloalkenyl, cycloalkenyloxy, cycloalkyl, cycloalkyloxy, hydroxy, —SO 2 NR 4 R 5 , —NR 4 SO 2 R 5 , —NR 4 R 5 , —C(═O)R 5 , —C(═O)C(═O)R 5 , —C(═O)NR 4 R 5 , —C(═O)OR 5 , —O(C═O)NR 4 R 5 , or —NR 4 C(═O)R 5 ; R 3 represents —C(═Z)—N(R 7 )R 6 ; A 1 represents a straight or branched C 1-6 alkylene chain optionally substituted by hydroxyl, alkoxy, oxo, cycloalkyl, aryl or heteroaryl; Z 1 represents a direct bond, an oxygen or sulphur atom or NH; n is zero; and mis 1; and N-oxides thereof, and their prodrugs, and pharmaceutically acceptable salts and solvates of the compounds of formula (I) and N-oxides thereof, and their prodrugs. Such compounds inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. The invention is also directed to pharmaceutical compositions comprising compounds of formula (I), their pharmaceutical use and methods for their preparation.

  本发明涉及公式（I）的生理活性化合物，其中2表示一个由9个环成的双环环系统，在该环3中为噁唑环，环4为苯环; R1表示氢或1至约4个碳原子的直链或支链烷基，可选地被羟基或一个或多个卤素原子取代，或当Z1表示直接键时，R1也可以表示低烯基或低炔基或甲酰基; R2表示氢、烯基、烷氧基、烷基、烷基磺酰基、烷基磺酰基、烷基硫基、芳基、芳基烷氧基、芳基烷基磺酰基、芳基烷基磺酰基、芳基烷基硫基、芳氧基、芳基磺酰基、芳基磺酰基、芳基硫基、氰基、环烯基、环烯基氧基、环烷基、环烷基氧基、羟基、-SO2NR4R5、-NR4SO2R5、-NR4R5、-C(═O)R5、-C(═O)C(═O)R5、-C(═O)NR4R5、-C(═O)OR5、-O(C═O)NR4R5或-NR4C(═O)R5; R3表示-C(═Z)-N(R7)R6; A1表示一条直链或支链C1-6烷基链，可选地被羟基、烷氧基、氧代、环烷基、芳基或杂环芳基取代; Z1表示直接键、氧原子或硫原子或NH; n为零; m为1;及其N-氧化物，以及公式（I）化合物和其N-氧化物的前药体，以及它们的制药可接受的盐和溶剂。这些化合物抑制TNF的产生或生理效应，并抑制环磷酸腺苷磷酸二酯酶。本发明还涉及包括公式（I）化合物的制药组合物，其制药用途和制备方法。