trypophostin A9 | 66023-14-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trypophostin A9
• 英文别名: 3,5-Di-t-butyl-4-hydroxybenzylmalodinitril；[(3,5-Di-tert-butyl-4-hydroxyphenyl)methyl]propanedinitrile；2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedinitrile
• CAS: 66023-14-1
• 化学式: C₁₈H₂₄N₂O
• 分子量: 284.401
• InChiKey: SSJFBOPXDKQBGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  67.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Coordinated metabolic reprogramming in response to productive viral infections
  申请人：ST. JUDE CHILDREN'S RESEARCH HOSPITAL

  公开号：US11083725B2

  公开（公告）日：2021-08-10

  The invention generally relates to methods of treating viral infections using known drugs and pharmaceutical compositions comprising same. More specifically, the disclosed methods are useful for the treatment of viral infections that are enveloped viruses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明一般涉及使用已知药物和包含已知药物的药物组合物治疗病毒感染的方法。更具体地说，所公开的方法可用于治疗包膜病毒感染。本摘要旨在作为一种扫描工具，用于在特定技术领域进行搜索，而无意限制本发明。
• COORDINATED METABOLIC REPROGRAMMING IN RESPONSE TO PRODUCTIVE VIRAL INFECTIONS
  申请人：ST. JUDE CHILDREN'S RESEARCH HOSPITAL

  公开号：US20170304293A1

  公开（公告）日：2017-10-26

  The invention generally relates to methods of treating viral infections using known drugs and pharmaceutical compositions comprising same. More specifically, the disclosed methods are useful for the treatment of viral infections that are enveloped viruses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• Coordinated Metabolic Reprogramming in Response to Productive Viral Infections
  申请人：St. Jude Children's Research Hospital

  公开号：US20210299118A1

  公开（公告）日：2021-09-30

  The invention generally relates to methods of treating viral infections using known drugs and pharmaceutical compositions comprising same. More specifically, the disclosed methods are useful for the treatment of viral infections that are enveloped viruses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.