Thenylfentanyl | 122861-39-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Thenylfentanyl
• 英文别名: N-phenyl-N-[1-(thiophen-2-ylmethyl)piperidin-4-yl]propanamide
• CAS: 122861-39-6
• 化学式: C₁₉H₂₄N₂OS
• 分子量: 328.5
• InChiKey: JSOSWRYHPGIWGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN
  申请人：Board Of Regents Of the University Of Texas System

  公开号：EP3468540A1

  公开（公告）日：2019-04-17
• NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
  申请人：Adapt Pharma Limited

  公开号：US20170071851A1

  公开（公告）日：2017-03-16

  Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
• [EN] METHOD FOR USING EXHALED BREATH TO DETERMINE THE PRESENCE OF DRUG<br/>[FR] MÉTHODE D'UTILISATION DE L'AIR EXPIRÉ POUR DÉTERMINER LA PRÉSENCE DE DROGUE
  申请人：PULMONARY ANALYTICS

  公开号：WO2014153099A2

  公开（公告）日：2014-09-25

  The present invention provides a method for determining the presence and/or the level of drug in a subject's system using exhaled breath of the subject.
• [EN] PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN<br/>[FR] COMPOSITIONS PHARMACEUTIQUES ET MÉTHODES DE TRAITEMENT DU CANCER
  申请人：UNIV TEXAS

  公开号：WO2017218518A1

  公开（公告）日：2017-12-21

  Compositions and methods for treatment of acute and chronic pain are disclosed herein. These compositions include fixed dose oral formulations containing an atypical antipsychotic drug and an opioid. Also provided here are methods of treatment of pain, particularly chronic pain while attenuating the abuse-liability of prescription pain medications.