2,2-Difluoro-3-methylpentane | 74185-71-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 2,2-Difluoro-3-methylpentane
• CAS: 74185-71-0
• 化学式: C₆H₁₂F₂
• 分子量: 122.16
• InChiKey: NSBQAUADNQVRNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL
  申请人：Sumitomo Chemical Company, Limited

  公开号：US20180009778A1

  公开（公告）日：2018-01-11

  Provided is a bipyridine compound that exhibits an excellent controlling effect against noxious arthropods. In particular, provided is a bipyridine compound of formula (I) or an N-oxide thereof in which the variable groups are as defined in the specification. Also provided are compositions containing the biypridine compound or an N-oxide thereof, and methods of using such compounds and compositions to control noxious arthropods.

  提供了一种双吡啶化合物，对有害节肢动物具有出色的控制效果。具体来说，提供的是式（I）或其N-氧化物的双吡啶化合物，其中变量基如规范中所定义。还提供了含有双吡啶化合物或其N-氧化物的组合物，以及使用这些化合物和组合物来控制有害节肢动物的方法。
• 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES
  申请人：Selles Patrice

  公开号：US20100184598A1

  公开（公告）日：2010-07-22

  The present invention relates to a method of preventing and/or controlling fungal infection in plants and/or plant propagation material comprising applying to the plant or plant propagation material a fungicidally effective amount of a compound of formula (I) or a salt of N-oxide thereof. In addition, the present invention also relates to a compound of formula (I).

  本发明涉及一种防止和/或控制植物和/或植物繁殖材料真菌感染的方法，包括向植物或植物繁殖材料施加化合物(I)或其N-氧化物盐的杀菌有效量。此外，本发明还涉及化合物(I)的一种。
• 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES
  申请人：Ohata Satoru

  公开号：US20100210704A1

  公开（公告）日：2010-08-19

  To provide pesticides such as insecticides, miticides and nematicides, which are excellent in the safety, pesticidal effects, residual effectiveness, etc., which further have infiltration, and which can be applied by soil treatment. A pesticide comprising a 3-alkoxy-1-phenyl-pyrazole derivative represented by the formula [I] or an agriculturally acceptable salt thereof as an active ingredient: wherein, for example, R 1 is a C 1 -C 10 alkyl group or the like, R 2 is a hydrogen atom or the like, R 3 is a hydrogen atom or the like, and each of R 4 , R 5 , R 6 and R 8 which are independent of one another, is a hydrogen atom or the like, and R 7 is a C 2 -C 4 haloalkylthio group or the like.

  提供杀虫剂，如杀虫剂，杀螨剂和杀线虫剂，这些杀虫剂在安全性、杀虫效果、残留效果等方面都非常出色，而且具有渗透性，可以通过土壤处理应用的杀虫剂。该杀虫剂包括以下公式[I]所表示的3-烷氧基-1-苯基-吡唑烷衍生物或其农业上可接受的盐作为活性成分：其中，例如，R1是C1-C10烷基或类似物，R2是氢原子或类似物，R3是氢原子或类似物，而且独立于彼此的R4、R5、R6和R8是氢原子或类似物，而R7是C2-C4卤代烷基硫基或类似物。
• PHARMACEUTICAL COMPOSITION COMPRISING A JAK-INHIBITING 4,6-SUBSTITUTED-PYRAZOLO[1,5-A]PYRAZINE COMPOUND
  申请人：Array Biopharma Inc.

  公开号：EP3878451A1

  公开（公告）日：2021-09-15

  Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3 and R4 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase-associated diseases and disorders, such as autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.

  式 I 的化合物： 及其立体异构体和药学上可接受的盐及溶液，其中 R1、R2、R3 和 R4 具有说明书中给出的含义，是一种或多种 JAK 激酶的抑制剂，可用于治疗与 JAK 激酶相关的疾病和紊乱，如自身免疫性疾病、炎症性疾病、移植器官、组织和细胞的排斥反应，以及血液病和恶性肿瘤及其并发症。
• 4,6-SUBSTITUTED-PYRAZOLO[1,5-A]PYRAZINES AS JANUS KINASE INHIBITORS
  申请人：Array Biopharma, Inc.

  公开号：EP3227297B1

  公开（公告）日：2021-01-20