cis-2,4-Dimethyl-penten-(2)-nitril | 19124-17-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: cis-2,4-Dimethyl-penten-(2)-nitril
• 英文别名: 2,4-Dimethyl-2-pentenenitrile, (Z)-；(Z)-2,4-dimethylpent-2-enenitrile
• CAS: 19124-17-5
• 化学式: C₇H₁₁N
• 分子量: 109.171
• InChiKey: BDAQROGLFIAJKL-DAXSKMNVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  23.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  cis-2,4-Dimethyl-penten-(2)-nitril 在 potassium tert-butylate 作用下， 以 氘代苯 为溶剂， 生成 trans-2,4-Dimethyl-penten-(2)-nitril 、 2,4-Dimethyl-pent-3-enenitrile 、 2,4-dimethyl-4-pentenenitrile
  参考文献：
  名称：

  1,3-Dicyano-5-phenyl-4,4-d2-hexa-2,5-diene 的 CryptoCope 重排。变色龙还是半人马座？

  摘要：

  用于评估自由基稳定扰动对 Cope 重排影响的“半人马座”模型推测取代基的独立作用，这些取代基对过渡区的两半提出了相互冲突的电子需求。该猜想的当前测试将 1,3-二氰基-[5-protio]-hexa-1,5-二烯 (1(H)) 和 2-苯基六-1,5-二烯与 1,3-二氰基- 5-苯基六-1,5-二烯 (1(Ph))。适当比较所需的热化学信息包括有关氰基与碳-碳双键共轭相互作用的 van't Hoff 型新数据、重新评估氰基在仲自由基和烯丙基自由基上的自由基稳定潜力、与（重新评估）氰基在 Cope 过渡区“节点”位置的稳定作用，

  DOI：

  10.1021/ja992137z

文献信息

• KINASE INHIBITORS
  申请人：Taunton, JR. John William

  公开号：US20130035325A1

  公开（公告）日：2013-02-07

  Methods of inhibiting kinases using kinase inhibitors having olefin moieties are disclosed.

  使用具有烯烃基团的激酶抑制剂抑制激酶的方法被披露。
• MOLECULES PRESENTING DUAL EMISSION PROPERTIES
  申请人：Université de Strasbourg

  公开号：US20170207400A1

  公开（公告）日：2017-07-20

  The present invention concerns compound of formula (I): wherein: A represents an electron-withdrawing group; D represents an electron-donating group; X is selected from the group consisting of: O, S and NR, wherein R is selected from the group consisting of: H, an alkyl group preferably comprising from 1 to 20 carbon atoms, an aryl group preferably comprising from 6 to 22 carbon atoms, and a heteroaryl group; n is an integer from 1 to 4; m is an integer from 1 to 6, preferably from 1 to 4; formula (II) represents a condensed bicyclic aromatic radical comprising from 6 to 22 carbon atoms, and from 1 to 3 heteroatom(s) selected from the group consisting of: N, S and O; the OH group being in ortho position of the condensed bicyclic aromatic radical relative to the formula (III) radical. The present invention also concerns its uses, and light devices comprising them.
• REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND FILMS MADE THEREFROM
  申请人：Eastman Chemical Company

  公开号：US20170306054A1

  公开（公告）日：2017-10-26

  Regioselectively substituted cellulose esters having a plurality of pivaloyl substituents and a plurality of aryl-acyl substituents are disclosed along with methods for making the same. Such cellulose esters may be suitable for use in films, such as +A optical films, and/or +C optical films. Optical films prepared employing such cellulose esters have a variety of commercial applications, such as, for example, as compensation films in liquid crystal displays and/or waveplates in creating circular polarized light used in 3-D technology.
• US9505766B2
  申请人：——

  公开号：US9505766B2

  公开（公告）日：2016-11-29
• [EN] NOVEL TRIAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME<br/>[FR] NOUVEAU DÉRIVÉ DE TRIAZOLOPYRIDINE ET COMPOSITION PHARMACEUTIQUE LE COMPRENANT<br/>[KO] 신규한 트리아졸로피리딘 유도체 및 이를 포함하는 약학 조성물
  申请人：DAE WOONG PHARMA

  公开号：WO2021107590A1

  公开（公告）日：2021-06-03

  본 발명은 하기 화학식 1로 표시되는 화합물, 또는 이의 약학적으로 허용 가능한 염에 관한 것으로, 본 발명에 따른 화합물은 카이네이즈 저해 작용이 유익한 질환의 예방 또는 치료에 유용하게 사용할 수 있다. 상기 화학식 1에서, R 1 내지 R 3는 명세서에서 정의한 바와 같다.