(5Z)-5-[(5-nitrofuran-2-yl)methylidene]imidazolidine-2,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: (5Z)-5-[(5-nitrofuran-2-yl)methylidene]imidazolidine-2,4-dione
• 化学式: C8H5N3O5
• 分子量: 223.14
• InChiKey: QFWCTABYNWDQLY-HYXAFXHYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• NITROFURANTOIN CONTROLLED RELEASE DOSAGE FORM
  申请人：RANBAXY LABORATORIES, LTD.

  公开号：EP1635794A2

  公开（公告）日：2006-03-22
• [EN] NITROFURANTOIN CONTROLLED RELEASE DOSAGE FORM<br/>[FR] FORME GALENIQUE A LIBERATION CONTROLEE DE NITROFURANTOINE
  申请人：RANBAXY LAB LTD

  公开号：WO2004017938A2

  公开（公告）日：2004-03-04

  The present invention generally relates to controlled release dosage forms which provide immediate release and sustained release of nitrofurantoin, and processes for their preparation. The controlled release dosage form includes a sustained release portion and an immediate release portion. The sustained release portion includes nitrofurantoin and one or more pH dependent hydrophilic polymers. The immediate release portion includes nitrofurantoin.