5-chloro-1,4-dimethyl-3-(trifluoromethyl)-1H-pyrazole | 261528-48-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 英文名称: 5-chloro-1,4-dimethyl-3-(trifluoromethyl)-1H-pyrazole
• 英文别名: 5-chloro-1,4-dimethyl-3-(trifluoromethyl)pyrazole
• CAS: 261528-48-7
• 化学式: C₆H₆ClF₃N₂
• 分子量: 198.57
• InChiKey: WWHFHGBVUYFBRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] FUNGICIDAL AMIDES<br/>[FR] AMIDES FONGICIDES
  申请人：DU PONT

  公开号：WO2014172190A1

  公开（公告）日：2014-10-23

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein A is a radical selected from the group consisting of A-1 through A-11, L is C(R12a)R12b-C(R13a)R13b; or 1,2-phenylene G is a radical selected from the group consisting of G-1, G-2, G-3, G-4, and G-5 and R1, R2, R12a, R12b, R13a, R13b and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.1

  揭示了Formula 1的化合物，包括所有立体异构体、N-氧化物和盐，其中A是从A-1到A-11组成的基团中选择的基团，L是C(R12a)R12b-C(R13a)R13b；或1,2-苯基，G是从G-1、G-2、G-3、G-4和G-5组成的基团中选择的基团，R1、R2、R12a、R12b、R13a、R13b和Q如本公开中所定义。还揭示了含有Formula 1化合物的组合物以及用于控制由真菌病原体引起的植物疾病的方法，包括施用本发明的化合物或组合物的有效量。
• Hexyl carboxanilides and their use for controlling undesirable micro-organisms
  申请人：Dunkel Ralf

  公开号：US20070037858A1

  公开（公告）日：2007-02-15

  The invention relates to novel hexylcarboxanilides of the formula (I) in which L, R 1 , R 3 and A are as defined in the disclosure, to a plurality of processes for preparing these compounds and their use for controlling unwanted microorganisms, and to novel intermediates and their preparation.

  本发明涉及一种新型的己基卡氧苯酰胺化合物，其化学式为(I)，其中L、R1、R3和A如本文所定义，以及制备这些化合物的多种方法以及它们用于控制不良微生物的用途，还涉及新型中间体及其制备。
• Fungicidal Composition Containing Acid Amide Derivative
  申请人：Nakamura Yuji

  公开号：US20080318779A1

  公开（公告）日：2008-12-25

  Conventional many fungicidal compositions have had practical problems such that either a preventive effect or a curing effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends to be inadequate depending upon the application site, and a fungicidal composition to overcome such problems has been desired. The present invention provides a fungicidal composition containing an acid amide derivative of the formula (I) or a salt thereof, as an active ingredient: wherein A is phenyl which may be substituted, benzyl which may be substituted, naphthyl which may be substituted, heterocyclic ring which may be substituted, fused heterocyclic ring which may be substituted, or the like; B is heterocyclic ring which may be substituted, fused heterocyclic ring which may be substituted, or naphthyl which may be substituted; each of R 1 and R 2 which are independent of each other, is alkyl, or the like; R 3 is hydrogen, or the like; each of W 1 and W 2 which are independent of each other, is oxygen or sulfur.

  传统的许多杀菌组合物存在实际问题，例如预防效果或治疗效果不足，残留效果倾向于不足，或者根据应用场所，对植物疾病的控制效果倾向于不足，因此需要一种克服这些问题的杀菌组合物。本发明提供了一种含有式(I)的酸酰胺衍生物或其盐作为活性成分的杀菌组合物：其中，A是苯基，可以是取代的苯基，苄基，可以是取代的苄基，萘基，可以是取代的萘基，杂环环，可以是取代的杂环环，融合的杂环环，可以是取代的融合的杂环环或类似物；B是杂环环，可以是取代的融合的杂环环或取代的萘基；R1和R2各自独立地是烷基或类似物；R3是氢或类似物；W1和W2各自独立地是氧或硫。
• Ethylene derivatives and pesticides containing said derivatives
  申请人：Ogura Tomoyuki

  公开号：US20070049495A1

  公开（公告）日：2007-03-01

  Ethylene derivatives of formula (I): where Q is an unsubstituted or substituted phenyl or heterocyclic group, especially a 4-thiazolyl, 1- or 3-pyrazolyl, 1,3-oxazol-4-yl, phenyl or pyridyl group; E is a substituent such as a cyano group; A is a substituent such as a 4-pyrazolyl or thiazolyl group; and B is a substituent such as an alkylcarbonyl group. Agricultural chemicals and agents for preventing the attachment of aquatic organisms containing one or more such ethylene derivatives.

  公式（I）的乙烯衍生物： 其中Q是未取代或取代的苯基或杂环基团，特别是4-噻唑基，1-或3-吡唑基，1,3-噁唑-4-基，苯基或吡啶基；E是氰基等取代基；A是4-吡唑基或噻唑基等取代基；B是烷基羰基等取代基。含有一种或多种这种乙烯衍生物的农业化学品和防止水生生物附着的剂。
• Imine Compound
  申请人：Saito Shiuji

  公开号：US20080312435A1

  公开（公告）日：2008-12-18

  An imine compound represented by the formula: wherein A represents a heterocyclic group; R 1 , R 2 , an R 3 each represent a hydrogen atom, a halogen atom, a C 1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom(s), a C 3-10 cycloalkyl group, a C 1-6 haloalkyl group, a C 1-10 alkoxy group, etc.; R 4 represents an optionally substituted C 1-10 alkyl, C 2-6 alkenyl, or aryl group; R 5 represents a hydrogen atom, a C 1-10 alkoxy group, a C 1-6 haloalkyl group, an optionally substituted C 1-10 alkyl or C 2-6 alkenyl group, an optionally substituted aryl or heterocyclic group, etc.; W represents —CO—, —CO—CO—, —CO—NH—, —CS—NH—, or —SO 2 —, or a cannabinoid-receptor agonist comprising said imine compound as an active ingredient. The imine compound of the present invention has a cannabinoid-receptor agonist effect, and is useful as a therapeutic or prophylactic drug for pains and autoimmune diseases.

  一种以以下式表示的亚胺化合物：其中A代表杂环基团；R1、R2和R3分别表示氢原子、卤素原子、C1-10烷基，该烷基可选地取代有芳基，所述芳基取代有卤素原子，C3-10环烷基，C1-6卤代烷基，C1-10烷氧基等；R4表示可选地取代的C1-10烷基，C2-6烯基或芳基；R5表示氢原子，C1-10烷氧基，C1-6卤代烷基，可选地取代的C1-10烷基或C2-6烯基，可选地取代的芳基或杂环基团等；W表示—CO—，—CO—CO—，—CO—NH—，—CS—NH—或—SO2—，或以该亚胺化合物为活性成分的大麻素受体激动剂。本发明的亚胺化合物具有大麻素受体激动剂作用，可用作治疗或预防疼痛和自身免疫性疾病的药物。