Benzyl (4-aminobutan-2-yl)carbamate hydrochloride | 1965309-06-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl (4-aminobutan-2-yl)carbamate hydrochloride
• 英文别名: benzyl N-(4-aminobutan-2-yl)carbamate;hydrochloride
• CAS: 1965309-06-1
• 化学式: C12H19ClN2O2
• 分子量: 258.74
• InChiKey: UJJNQMABWBCAOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.07
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  64.4
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Heterocyclic aromatic compounds useful as growth hormone secreagogues
  申请人：——

  公开号：US20040072881A1

  公开（公告）日：2004-04-15

  Heterocyclic aromatic compounds are provided which are useful in stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength. The heterocyclic aromatic compounds have the structure 1 including pharmaceutically acceptable salts thereof and all stereoisomers thereof, wherein X a is heteroaryl, preferably, 2 and R 1 , R 1a , R 6 , Y, X b , A, B, Z, R 3 , R 4 , R 4a , R 5 and R 5a are as defined herein.

  提供的杂环芳香族化合物可用于刺激内源性生长激素的产生或释放，治疗肥胖症、骨质疏松症（提高骨密度）以及提高肌肉质量和肌肉力量。 杂环芳香族化合物的结构如下 1 包括其药学上可接受的盐类及其所有立体异构体、 其中 X a 是杂芳基，优选 2 和 R 1 , R 1a , R 6 ，Y，X b , A, B, Z, R 3 , R 4 , R 4a , R 5 和 R 5a 如本文所定义。
• EP1175213A4
  申请人：——

  公开号：EP1175213A4

  公开（公告）日：2007-04-11
• HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP1175213A2

  公开（公告）日：2002-01-30
• Heterocyclic aromatic compounds useful as growth hormone secretagogues
  申请人：——

  公开号：US20040002525A1

  公开（公告）日：2004-01-01

  Heterocyclic aromatic compounds are provided which are useful in stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength. The heterocyclic aromatic compounds have the structure 1 including pharmaceutically acceptable salts thereof and all stereoisomers thereof, wherein X a is heteroaryl, preferably, 2 and R 1 , R 1a , R 6 , Y, X b , A, B, Z, R 3 , R 4 , R 4a , R 5 and R 5a are as defined herein.
• US6518292B1
  申请人：——

  公开号：US6518292B1

  公开（公告）日：2003-02-11