5-Phenyl-5-methylcapronsaeure | 132858-57-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-Phenyl-5-methylcapronsaeure
• 英文别名: 5-methyl-5-phenyl-hexanoic acid；5-Methyl-5-phenyl-hexansaeure；5-Methyl-5-phenylhexanoic acid
• CAS: 132858-57-2
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: LVRBXMINJNZHAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-Phenyl-5-methylcapronsaeure 在 PPA 作用下， 反应 1.0h， 生成 9,9-dimethyl-6,7,8,9-tetrahydro-benzocyclohepten-5-one
  参考文献：
  名称：

  Substituted guanidine derivatives and process for producing the same

  摘要：

  通式（1）所代表的化合物： 其中R1、R2、R3、R4和R5中的每一个是氢原子、烷基、取代烷基、烯基、炔基、环烷基、环烯基、饱和杂环基、芳香基、酰基或类似物；Y1、Y2、Y3和Y4中的每一个是单键、—CH2—、—O—、—CO—或类似物，前提是至少两个Y1到Y4中的独立团是单键以外的团；以及Z可以不存在，或者一个或多个Z可以存在且独立地是烷基、取代烷基、烯基、炔基、环烷基、环烯基、饱和杂环基、卤素原子、羧基、烷氧羰基、芳香基、酰基或类似物，对于由于钠/质子交换传输系统加速而引起的疾病，具有治疗或预防作用。

  公开号：

  US06369110B1
• 作为产物：
  描述：

  3-甲基-3-苯基丁烷-1-醇 生成 5-Phenyl-5-methylcapronsaeure
  参考文献：
  名称：

  Julia et al., Bulletin de la Societe Chimique de France, 1959, p. 1449,1452

  摘要：

  DOI：

文献信息

• Aminoethanol derivatives
  申请人：——

  公开号：US20040127574A1

  公开（公告）日：2004-07-01

  The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formula 1 wherein Ar 1 is an aromatic ring group optionally having substituents, Ar 2 is an aromatic ring group having substituents, OR″ is an optionally protected hydroxyl group, R is an acyl group, R′ is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.

  本发明提供了一种具有胆固醇酯转移蛋白抑制作用的药物剂，可用作降低血脂等方面的药物。本发明涉及一种由式1表示的化合物，其中Ar1是一个带有取代基的芳香环基团，Ar2是一个带有取代基的芳香环基团，OR″是一个可选保护的羟基，R是一个酰基，R′是一个氢原子或一个可选带有取代基的碳氢基团，或其盐，以及含有式(I)的化合物或其盐或前药的药物组合物。
• AMINOETHANOL DERIVATIVES
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP1362846A1

  公开（公告）日：2003-11-19

  The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formula wherein Ar1 is an aromatic ring group optionally having substituents, Ar2 is an aromatic ring group having substituents, OR'' is an optionally protected hydroxyl group, R is an acyl group, R' is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.

  本发明提供了一种具有胆固醇酯转移蛋白抑制作用的药剂，可用作降血脂药等。本发明涉及一种由式表示的化合物 其中 Ar1 是可选具有取代基的芳香环基，Ar2 是可选具有取代基的芳香环基，OR''是可选保护的羟基，R 是酰基，R'是氢原子或可选具有取代基的烃基，或其盐，以及含有式（I）化合物或其盐或其原药的药物组合物。
• Fullerene Multi-Adduct Compositions
  申请人：Hummelen Jan C.

  公开号：US20110089380A1

  公开（公告）日：2011-04-21

  One aspect of the invention relates to compositions comprising one or more fullerene derivatives that comprise one or more covalent addends. In certain embodiments, the fullerene derivatives are selected from the group consisting of methanofullerene derivatives, Prato adduct fullerene derivatives, Diels-Alder fullerene derivatives, diazoline fullerene derivatives, Bingel fullerene derivatives, ketolactam fullerene derivatives, and azafulleroid fullerene derivatives. In certain embodiments, the fullerenes are C60 or C70 or a mixture thereof. The invention also relates to semiconductors, photodiodes, solar cells, photodectectors, and transistors comprising one or more fullerene derivatives that comprise one or more covalent addends.
• POLYMER COMPOUND HAVING CARBON CLUSTER STRUCTURE AND ORGANIC DEVICE USING SAME
  申请人：Tanaka Shin-Ya

  公开号：US20130270545A1

  公开（公告）日：2013-10-17

  A polymer compound, is provided in which at least a part of repeating units has a group containing a carbon cluster structure. The polymer compound preferably one or more, more preferably two or more, units selected from an arylene unit, a heteroarylene unit and an aromatic amine unit, as repeating units.
• US6982348B2
  申请人：——

  公开号：US6982348B2

  公开（公告）日：2006-01-03