2,2',3,3'-Tetrachlorodiphenyl ether | 727738-46-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2',3,3'-Tetrachlorodiphenyl ether
• 英文别名: 1,2-dichloro-3-(2,3-dichlorophenoxy)benzene
• CAS: 727738-46-7
• 化学式: C₁₂H₆Cl₄O
• 分子量: 308.0
• InChiKey: WXEOWWVZWWGBBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] OXIME ESTER PHOTOINITIATORS<br/>[FR] PHOTOINITIATEURS À BASE D'ESTER D'OXIME
  申请人：BASF SE

  公开号：WO2015004565A1

  公开（公告）日：2015-01-15

  Compounds of the formula (I) n, wherein Q is a direct bond or an n-valent linking group; n is an integer 2, 3, or 4; Z is for example C1-C20alkylene, C2-C20alkenylene,C5-C8 cycloalkylene or C5-C8 cycloalkenylene; Y is for example C6-C20aryl or C3-C20heteroaryl; R1 is for example hydrogen, C2-C5alkenyl, C3-C8cycloalkyl, C1-C12alkyl, phenyl, naphthyl, C3-C20heteroaryl, C1-C8alkoxy, benzyloxy or phenoxy; R2 is for example C1-C20alkyl, C2-C12alkenyl, C4-C8cycloalkenyl, C2-C12alkinyl, C3-C10cycloalkyl, phenyl or naphthyl; R15, R16, R17, R18, R19 and R20 independently of each other for example are hydrogen, halogen, C1-C20alkyl, C6-C20aryl or C4-C20heteroaryl; provided that a compound wherein R15, R16, R17, R18, R19 and R20 are hydrogen, Y is thienyl, R1 is methyl, R2 is ethyl, n is 2, Q is a direct bond and Z is n-propylene and a compound wherein R15, R16, R17, R18, R19 and R20 are hydrogen, Y is thienyl, R1 is methyl, R2 is ethyl, n is 2, Q as an n-valent linking group is methylene and Z is methylene are excluded; are reactive photoinitiators in particular in electronic applications.

  化合物的公式（I）n，其中Q是直接键或n价键合基团；n是整数2、3或4；Z例如是C1-C20烷基，C2-C20烯基，C5-C8环烷基或C5-C8环烯基；Y例如是C6-C20芳基或C3-C20杂环芳基；R1例如是氢，C2-C5烯基，C3-C8环烷基，C1-C12烷基，苯基，萘基，C3-C20杂环芳基，C1-C8烷氧基，苄氧基或苯氧基；R2例如是C1-C20烷基，C2-C12烯基，C4-C8环烯基，C2-C12炔基，C3-C10环烷基，苯基或萘基；R15、R16、R17、R18、R19和R20彼此独立地例如是氢，卤素，C1-C20烷基，C6-C20芳基或C4-C20杂环芳基；前提是化合物中R15、R16、R17、R18、R19和R20为氢，Y为噻吩基，R1为甲基，R2为乙基，n为2，Q为直接键，Z为n-丙烯基和化合物中R15、R16、R17、R18、R19和R20为氢，Y为噻吩基，R1为甲基，R2为乙基，n为2，Q作为n价键合基团为亚甲基，Z为亚甲基被排除；在特定电子应用中是具有反应性的光引发剂。
• COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS
  申请人：Brandeis University

  公开号：US20150210727A1

  公开（公告）日：2015-07-30

  Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful as inhibitors of IMPDH. In certain embodiments, a compound selectively inhibits a parasitic IMPDH versus a host IMPDH. Also disclosed are pharmaceutical compositions comprising one or more compounds of the invention. Related methods of treating various parasitic and bacterial infections in mammals are disclosed. Moreover, the compounds may be used alone or in combination with other therapeutic or prophylactic agents, such as anti-virals, anti-inflammatory agents, antimicrobials and immunosuppressants.

  本发明公开了一种化合物及其药学上可接受的盐，它们可用作IMPDH的抑制剂。在某些实施例中，该化合物选择性地抑制寄生IMPDH而不影响宿主IMPDH。本发明还公开了包含本发明中一种或多种化合物的制药组合物。公开了治疗哺乳动物中各种寄生虫和细菌感染的相关方法。此外，这些化合物可单独或与其他治疗或预防药物，如抗病毒药物、抗炎药物、抗微生物药物和免疫抑制剂一起使用。
• Method for purifying an organic solvent for the purposes of absorption of maleic acid anhydride
  申请人：——

  公开号：US20040127726A1

  公开（公告）日：2004-07-01

  In a process for purifying an organic solvent for the absorption of maleic anhydride from a gaseous mixture, in which the maleic anhydride is separated off from the solvent, a substream is taken from the solvent stream, this substream is distilled and returned to the solvent circuit, the proposed improvement comprises separating off a low-boiling fraction and a high-boiling fraction from the fraction consisting essentially of purified solvent and feeding the fraction consisting essentially of purified solvent back into the solvent stream.

  在一种用于从气态混合物中吸收顺丁烯二酸酐的有机溶剂的提纯工艺中，顺丁烯二酸酐从溶剂中分离出来，从溶剂流中提取一个子流，这个子流经过蒸馏后返回溶剂回路，建议的改进包括从主要由提纯溶剂组成的馏分中分离出一个低沸点馏分和一个高沸点馏分，并将主要由提纯溶剂组成的馏分送回溶剂流。
• OXIME ESTER PHOTOINITIATORS
  申请人：BASF SE

  公开号：EP3019473A1

  公开（公告）日：2016-05-18
• LIGAND-MODIFIED FILTER AND METHODS FOR REDUCING METALS FROM LIQUID COMPOSITIONS
  申请人：Entegris, Inc.

  公开号：EP3921067A1

  公开（公告）日：2021-12-15