[EN] NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE<br/>[FR] AGENTS ANTI-GNRH NON PEPTIDIQUES, COMPOSITIONS PHARMACEUTIQUES ET PROCEDES D'UTILISATION
申请人:PFIZER
公开号:WO2003106446A1
公开(公告)日:2003-12-24
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing
hormone are described. Such compounds and their pharmaceutically acceptable
salts, prodrugs, and active metabolites are suitable for treating mammalian
reproductive disorders and steroid hormone-dependent tumors as well as for
regulating fertility, where suppression o£ gonadotropin release is indicated.
Methods for synthesizing the compounds and intermediates useful in their preparation
are also described.