4-ethenyl-4'-(4-pentylcyclohexyl)-1,1'-biphenyl | 1209494-56-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-ethenyl-4'-(4-pentylcyclohexyl)-1,1'-biphenyl
• 英文别名: 1-Ethenyl-4-[4-(4-pentylcyclohexyl)phenyl]benzene
• CAS: 1209494-56-3
• 化学式: C₂₅H₃₂
• 分子量: 332.529
• InChiKey: QGZSAOZFHYYUMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  4-乙烯基苯硼酸 、 1-bromo-4-(4-pentylcyclohexyl)benzene 在 potassium phosphate monohydrate 、 C₆H₁₄Cl₂N₂Pd⁽¹⁺⁾ 作用下， 以 甲苯 为溶剂， 反应 6.0h， 以84%的产率得到4-ethenyl-4'-(4-pentylcyclohexyl)-1,1'-biphenyl
  参考文献：
  名称：

  Synthesis of 4-Vinylbiphenyl Derivatives by Pd(II)-1,2-Diamino-cyclohexane Complex Catalyzed Suzuki-Miyaura Reaction

  摘要：

  一系列4-乙烯基联苯衍生物通过Pd(II)-1,2-二氨基环己烷复合催化的铃木-宫浦反应合成，在80℃的甲苯中以K3PO4·3H2O作为碱，得到的产物收率为39-95%。根据这一高效的C-C键形成方法，获得的4-乙烯基联苯液晶化合物的收率高达89%。

  DOI：

  10.14233/ajchem.2014.16972

文献信息

• A rapid and efficient catalysis system for the synthesis of 4-vinylbiphenyl derivatives
  作者：Xiaowei Ma、Yan Liu、Ping Liu、Jianwei Xie、Bin Dai、Zhiyong Liu

  DOI：10.1002/aoc.3045

  日期：2013.12

  A series of 4‐vinylbiphenyl derivatives were synthesized by Pd(OAc)2/PCy3‐catalyzed Suzuki–Miyaura reaction in the presence of K3PO4.3H2O as base in toluene at 80°C for only 10–30 min, and the corresponding products achieved 65–98% yields. According to this efficient C―C bond‐forming method, the obtained yields of 4‐vinylbiphenyl liquid crystal compounds were up to 92–96%. Copyright © 2013 John Wiley

  在甲苯中以K 3 PO 4 .3H 2 O为碱的情况下，在80°C下仅10-30分钟的时间内，通过Pd（OAc）2 / PCy 3催化的Suzuki-Miyaura反应合成了一系列4-乙烯基联苯衍生物。，相应的产品可达到65-98％的收率。根据这种有效的CC键形成方法，获得的4-乙烯基联苯液晶化合物的产率高达92-96％。版权所有©2013 John Wiley＆Sons，Ltd.
• Synthesis of 4-Substituted Styrene Compounds via Palladium-Catalyzed Suzuki Coupling Reaction Using Free Phosphine Ligand in Air
  作者：Yan Liu、Jinqu Wang

  DOI：10.1080/00397910902883611

  日期：2009.12.30

  The air-stable and easy to prepare nonsymmetric Schiff base ligands have been synthesized and proven to be efficient ligands for Suzuki cross-coupling reaction between aryl bromides and arylboronic acids using PdCl2(CH3CN)2 as palladium source under aerobic conditions. The coupling reaction proceeded smoothly using N-[(3,4-dimethoxyphenyl)methylene]-1,2-benzenediamine (L3) as ligand under mild conditions to provide 4-substituted styrene compounds in good yields.
• Synthesis of 4-Vinylbiphenyl Derivatives by Pd(II)-1,2-Diamino-cyclohexane Complex Catalyzed Suzuki-Miyaura Reaction
  作者：Y. Liu、X.W. Ma、P. Liu、J.W. Xie、B. Dai

  DOI：10.14233/ajchem.2014.16972

  日期：——

  A series of 4-vinylbiphenyl derivatives were synthesized by Pd(II)-1,2-diaminocyclohexane complex catalyzed Suzuki-Miyaura reactions in the presence of K3PO4·3H2O as base in toluene at 80 °C and the corresponding products achieved 39-95 % yields. According to this efficient C-C bond-forming method, the obtained yields of 4-vinylbiphenyl liquid crystal compounds were up to 89 %.

  一系列4-乙烯基联苯衍生物通过Pd(II)-1,2-二氨基环己烷复合催化的铃木-宫浦反应合成，在80℃的甲苯中以K3PO4·3H2O作为碱，得到的产物收率为39-95%。根据这一高效的C-C键形成方法，获得的4-乙烯基联苯液晶化合物的收率高达89%。