Bis(3,4,5-trihydroxyphenyl)methanone | 111621-53-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Bis(3,4,5-trihydroxyphenyl)methanone
• CAS: 111621-53-5
• 化学式: C₁₃H₁₀O₇
• 分子量: 278.21
• InChiKey: IGKOKEBHGRCHSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  138
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• [EN] COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS<br/>[FR] COMPOSITIONS DE BENZOPHÉNONES POLYHYDROXYLÉS ET MÉTHODES DE TRAITEMENT DE TROUBLES NEURODÉGÉNÉRATIFS
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2017106861A1

  公开（公告）日：2017-06-22

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.

  本发明涉及聚羟基苯酮类化合物，其在治疗神经退行性、神经学、精神病和认知疾病中有用，特别是那些与HDAC1脱乙酰化酶活性缺乏有关的疾病。
• Composition for forming film protecting against aqueous hydrogen peroxide solution
  申请人：NISSAN CHEMICAL CORPORATION

  公开号：US10894887B2

  公开（公告）日：2021-01-19

  A composition for forming protective film against aqueous hydrogen peroxide solution, composition including resin; compound of following Formula (1a), (1b), or (1c): (wherein X is carbonyl group or methylene group; 1 and m are each independently integer of 0-5 to satisfy relation: 3≤1+m≤10; n is integer of 2-5; u and v are each independently integer of 0-4 to satisfy relation: 3≤u+v≤8; R1-R4 are each independently hydrogen atom, hydroxy group, C1-10 hydrocarbon group, or C6-20 aryl group; when R1-R4 are each the C1-10 hydrocarbon group; and j and k are each independently 0 or 1); crosslinking agent and catalyst; and solvent, wherein amount of compound of Formula (1a), (1b), or (1c) is at most 80% by mass relative to amount of resin, and amount of crosslinking agent is 5%-40% by mass relative to amount of resin.

  一种用于形成过氧化氢水溶液保护膜的组合物，该组合物包括树脂；下式 (1a)、(1b) 或 (1c) 的化合物： (其中 X 为羰基或亚甲基；1 和 m 各自独立地为 0-5 的整数，以满足以下关系：3≤1+m≤10；n 为 2-5 的整数；u 和 v 各自独立地为 0-4 的整数，以满足关系式： 3≤u+v≤8; R1-R4 各自独立地为氢原子：3≤u+v≤8；R1-R4各自独立地为氢原子、羟基、C1-10烃基或C6-20芳基；当R1-R4各自为C1-10烃基时；以及j和k各自独立地为0或1）；交联剂和催化剂；以及溶剂，其中式(1a)、(1b)或(1c)化合物的用量最多为树脂用量的80%，交联剂的用量为树脂用量的5%-40%。
• Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders
  申请人：Massachusetts Institute of Technology

  公开号：US11180438B2

  公开（公告）日：2021-11-23

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.

  本发明涉及多羟基二苯甲酮化合物，可用于治疗神经退行性疾病、神经疾病、精神疾病和认知疾病，特别是与 HDAC1 去乙酰化酶活性缺乏有关的疾病。
• JPH10324657A
  申请人：——

  公开号：JPH10324657A

  公开（公告）日：1998-12-08
• LIQUID CRYSTAL DISPLAY ELEMENT, POSITIVE TYPE RADIATION SENSITIVE COMPOSITION, INTERLAYER INSULATING FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT, AND FORMATION METHOD THEREOF
  申请人：ICHINOHE Daigo

  公开号：US20110281040A1

  公开（公告）日：2011-11-17

  Provided by the present invention is a liquid crystal display element including: two substrates disposed oppositely, an interlayer insulating film laminated on the inner face side of at least one of the substrates, and a liquid crystal layer being provided between the substrates, and being formed from a polymerizable liquid crystal composition, in which a resin constituting the interlayer insulating film has a crosslinking moiety of a polymer represented by the following formula (1):