[5-甲基-2-(三氟甲基)-3-呋喃基]甲基胺 | 823-77-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: [5-甲基-2-(三氟甲基)-3-呋喃基]甲基胺
• 中文别名: 二烟酸钙；烟酸钙
• 英文名称: 3-Pyridinecarboxylicacid, calcium salt (2:1)
• CAS: 823-77-8
• 化学式: C6H5CaNO2
• 分子量: 163.19
• InChiKey: ANAYXXGDTUJQKJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  50.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• HAEMOSTATIC AND WOUND HEALING MEDICINE
  申请人：Limited Liability Company "Tectum"

  公开号：EP3278815A1

  公开（公告）日：2018-02-07

  The present invention refers to medicine, namely hemostatic and wound healing agents, and can be used to stop bleeding of various severity, including venous, as well as to heal wounds and cuts obtained as a result of mechanical action on the epidermal and muscular layers of tissues. For this, a hemostatic agent containing an active gelling agent based on chitosan and / or its derivatives is used, characterized in that it contains chitosan, its salts and / or its derivatives in the form of a gel having a three-dimensional crosslinked structure as a polymer matrix and components of natural thrombus formation in the form of organic calcium compounds, organic acid and water coordinated on this matrix at a certain ratio of components. The technical result of the invention consists in accelerating the arrest of bleeding of various severity and creating an antibacterial effect.

  本发明指的是药物，即止血剂和伤口愈合剂，可用于止住各种严重程度的出血，包括静脉出血，以及愈合由于对组织表皮层和肌肉层的机械作用而造成的伤口和割伤。为此，使用了一种含有以壳聚糖和/或其衍生物为基础的活性胶凝剂的止血剂，其特征在于它含有壳聚糖、其盐和/或其衍生物，以具有三维交联结构的凝胶形式作为聚合物基质，以及以有机钙化合物、有机酸和水的形式按一定比例配位在该基质上的天然血栓形成成分。 本发明的技术成果包括加速止住各种严重程度的出血，并产生抗菌效果。
• Appetite suppressant compositions and methods thereof
  申请人：Red Mountain Holdings, LLC

  公开号：US11344556B2

  公开（公告）日：2022-05-31

  In various embodiments an appetite suppressant composition comprises at least one anorectic active ingredient (AAI); at least one of a nutritive substance, a controlled drug delivery agent (CDRA), and a cofactor; and optionally, an excipient. The AIA may comprise any one of phentermine, phendimetrazine, diethylpropion, naltrexone, and bupropion. The CDRA may comprise a cellulosic. The cofactor may comprise a chromium or selenium salt. In various embodiments, the compositions herein are provided in an oral capsule dosage form for GI-tract administration of the AAI. A method of suppressing appetite in individuals in need thereof are described.

  在各种实施方案中，食欲抑制剂组合物包括至少一种厌食症活性成分（AAI）；营养物质、控制给药剂（CDRA）和辅助因子中的至少一种；以及可选的赋形剂。AIA可包括芬特明、芬地美曲秦、地特丙酮、纳曲酮和安非他酮中的任意一种。CDRA 可包括纤维素。辅助因子可包括铬盐或硒盐。在各种实施方案中，本文中的组合物以口服胶囊剂型提供，用于胃肠道给药 AAI。描述了一种抑制需要者食欲的方法。
• Method for denaturing allergens
  申请人：——

  公开号：US20010048097A1

  公开（公告）日：2001-12-06

  Application of an alkaline earth metal salt selected from calcium and strontium salts can steadily denature the allergens those exist in the environment without any coloring trouble on the treated material.

  使用从钙盐和锶盐中选出的碱土金属盐可以稳定地使环境中存在的过敏原变性，而不会给处理过的材料带来任何着色问题。
• Method for denaturing allergens using calcium or strontium salts
  申请人：Sumitomo Chemical Co.,Ltd.

  公开号：EP1133918B1

  公开（公告）日：2004-09-08
• ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM SALTS
  申请人：Janssen Pharmaceutica, N.V.

  公开号：EP2323485A1

  公开（公告）日：2011-05-25